Evidence mapPaperPMID 41207012Full record

ReviewThe journal of gene medicine2025

Mechanisms of lncRNA in Diabetic Foot Ulcer Wound Healing.

Yiming Chen, Mengting Wang, Xiaoliang Cao, Shengfeng Gao, Yasu Jiang, Zhenhua Gong

Abstract readReview
In one paragraph

Review in The journal of gene medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yiming ChenMedical School, Nantong University, Nantong, China.ORCID 0009-0009-2226-5820
Mengting WangMedical School, Nantong University, Nantong, China.
Xiaoliang CaoMedical School, Nantong University, Nantong, China.
Shengfeng GaoDepartment of Burn and Plastic Surgery, Affiliated Hospital 2 of Nantong University, Nantong First People's Hospital, Nantong, China.
Yasu JiangDepartment of Burn and Plastic Surgery, Affiliated Hospital 2 of Nantong University, Nantong First People's Hospital, Nantong, China.
Zhenhua GongMedical School, Nantong University, Nantong, China.

Funding

Clinical project of Nantong University 2022JZ006Medical Research Project of Nantong Health Commission MS2022017Nantong Municipal Health Commission Scientific Research Project QNZ2024022Nantong Science and Technology Bureau QNZ2023023Nantong University Clinical Medicine Special Research Fund Project 2024JY007Science Foundation of Kangda College of Nanjing Medical University KD2022KYJJZD021
6 · The paper itself

Abstract

Diabetes mellitus (DM) is a chronic metabolic disease, and some diabetic patients develop diabetic foot ulcers (DFU), which are one of the most prevalent and serious complications among diabetic patients. These ulcers can lead to neuropathy, vasculopathy and severe infections. LncRNAs, a class of long-stranded noncoding RNAs that regulate gene expression, have been shown to play a critical regulatory role in diabetic foot ulcer wound healing. These molecules have been demonstrated to modulate numerous facets of the inflammatory response, cell proliferation and angiogenesis, which collectively influence the outcome of wound healing. A substantial body of research has emerged in recent years, highlighting the critical role of these noncoding transcripts in DFU. This paper reviews recent research advances on the regulatory functions and potential mechanisms of noncoding transcripts in the healing of diabetic foot ulcers, based on a literature search of databases such as PubMed and Web of Science over the past decade.

Indexed as

Diabetic FootRNA, Long NoncodingWound HealingAnimalsGene Expression RegulationHumansRNA, Long NoncodingdiabetesDNA technologyRNA technologies

Identifiers

PMID41207012
PMCPMC12597133

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.