Evidence map›Paper›PMID 41207786›Full record

ArticleZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences2025

[Gandou Bushen decoction ameliorates ovarian injury in murine hepatolenticular degeneration via the AGE/RAGE/NF-κB signaling pathway].

Pengyu Jiang, Limin Wu, Hui Han

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pengyu JiangBrain Disease Center, the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei 230031, China. 18297475477@163.com.
Limin WuRepro-ductive and Genetic Branch, the First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, China.
Hui HanBrain Disease Center, the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei 230031, China. hanhuidoctor2022@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the protective effect and underlying mechanism of Chinese herbal medicine Gandou Bushen decoction (GBD) on ovarian injury in murine hepatolenticular degeneration (HLD) model.

methodsThe chemical constituents of GBD were analyzed using liquid chromatography-mass spectrometry (LC-MS). Forty female C3He-

resultsA total of 1465 chemical components were identified in GBD. Compared with the normal control group, the model group showed decreased body weight, ovarian weight, and ovarian coefficient (all

conclusionsGBD ameliorates ovarian injury in HLD, and its mechanism of action is associated with the suppression of the AGE/RAGE/NF-κB signaling pathway.

Indexed as

Drugs, Chinese HerbalGlycation End Products, AdvancedNF-kappa BOvaryAnimalsFemaleMiceSignal TransductionDrugs, Chinese HerbalGlycation End Products, AdvancedNF-kappa BAGE/RAGE/NF-κB signaling pathwayCopper metabolismGandou Bushen decoctionGranular cellsHepatolenticular degenerationInjury of ovaryMiceOxidative stress

Identifiers

PMID41207786
PMCPMC12750057

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.