Trial reportTransplantation proceedings2025
Feasibility, Acceptability, and Satisfaction of a Lifestyle Intervention for Post-Transplant Weight Loss.
Trial report in Transplantation proceedings, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
11 authors.
Funding
Abstract
backgroundAbdominal organ transplant recipients with obesity can benefit from lifestyle modification interventions for weight loss. We aimed to assess the feasibility, acceptability, and appropriateness of a lifestyle modification intervention using connected health services (Fitbit and scale), coaching phone calls, and virtual group educational sessions.
methodsTwelve kidney transplant recipients and 12 liver transplant recipients received a Fitbit, weighting scale, and nutritional coaching calls for 12 months. Twelve participants were randomized to 5 educational group sessions on lifestyle modifications. Control patients who did not lose ≥2.5% of their body weight at 6 months were invited to crossover to the group sessions arm. Feasibility, acceptability, and appropriateness of the interventions were assessed at 6 months and 12 months.
resultsTwenty-four participants (median age, 57 years [interquartile range, 46.2-67.5 years], 75% male, a median of 24.9 months [IQR, 15.7-43.2]) months post-transplant) completed the study. The Fitbit wristband and scales were found to be 58% appropriate, 62.5% acceptable, and 67% feasible. Phone calls were found to be 50% appropriate, 54% acceptable, and 62.5% feasible. Attendance at ≥2 group sessions was achieved by 10 patients (62.5%; 7 from the intervention arm and 3 crossovers). Among these patients, 47% found the sessions acceptable, 59% appropriate, and 53% feasible.
conclusionTransplant recipients aiming for weight loss found the multicomponent lifestyle intervention feasible and acceptable. Larger studies are needed to test the effectiveness of these interventions.
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