Evidence mapPaperPMID 41208975Full record

ArticleFrontiers in immunology2025

The role of

Joao Carlos Batista-Liz, María Sebastián Mora-Gil, Mónica Renuncio García, María Teresa Leonardo, Ana Peñalba, Ligia Gabrie, Rafael Gálvez Sánchez, Luis Martín-Penagos, Javier Narvaez, Belén Sevilla-Pérez and 17 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Joao Carlos Batista-Liz *Immunopathology Group, Instituto de Investigación Marqués de Valdecilla (IDIVAL), Santander, Spain.
María Sebastián Mora-Gil *Immunopathology Group, Instituto de Investigación Marqués de Valdecilla (IDIVAL), Santander, Spain.
Mónica Renuncio GarcíaImmunology Unit, Complejo Asistencial Universitario de León, León, Spain.
María Teresa LeonardoDivision of Paediatrics, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
Ana PeñalbaDivision of Paediatrics, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
Ligia GabrieImmunopathology Group, Instituto de Investigación Marqués de Valdecilla (IDIVAL), Santander, Spain.
Rafael Gálvez SánchezImmunopathology Group, Instituto de Investigación Marqués de Valdecilla (IDIVAL), Santander, Spain.
Luis Martín-PenagosImmunopathology Group, Instituto de Investigación Marqués de Valdecilla (IDIVAL), Santander, Spain.
Javier NarvaezDivision of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain.
Belén Sevilla-PérezDivision of Paediatrics, Hospital Universitario Clínico San Cecilio, Granada, Spain.
Raquel Ríos FernándezSystemic Autoimmune Disease Unit, Hospital Universitario Clínico San Cecilio, Instituto de Investigación Biosanitaria Ibs.GRANADA, Granada, Spain.
José Luis Callejas-RubioSystemic Autoimmune Disease Unit, Hospital Universitario Clínico San Cecilio, Instituto de Investigación Biosanitaria Ibs.GRANADA, Granada, Spain.
Luis Caminal-MonteroInternal Medicine Department, Hospital Universitario Central de Asturias, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain.
Paz ColladoDivision of Rheumatology, Hospital Universitario Severo Ochoa, Madrid, Spain.
José Javier Pérez VenegasDivision of Rheumatology, Hospital General de Jerez, Jerez de la Frontera, Spain.
María José Rodríguez VallsDivision of Rheumatology, Hospital General de Jerez, Jerez de la Frontera, Spain.
Diego De ÁrgilaDivision of Dermatology, Hospital Universitario de La Princesa, Madrid, Spain.
Patricia Quiroga ColinaDivision of Rheumatology, Hospital Universitario de La Princesa, Instituto de Investigaciones Sanitarias (IIS)-Princesa, Universidad Autónoma de Madrid, Madrid, Spain.
Esther Francisca Vicente RabanedaDivision of Rheumatology, Hospital Universitario de La Princesa, Instituto de Investigaciones Sanitarias (IIS)-Princesa, Universidad Autónoma de Madrid, Madrid, Spain.
Esteban RubioDivision of Rheumatology, Hospital Universitario Virgen del Rocío, Sevilla, Spain.
Manuel León LuqueDivision of Rheumatology, Hospital Universitario Virgen del Rocío, Sevilla, Spain.
Juan María Blanco-MadrigalDivision of Rheumatology, Hospital Universitario de Basurto, Bilbao, Spain.
Eva Galíndez-AgirregoikoaDivision of Rheumatology, Hospital Universitario de Basurto, Bilbao, Spain.
Javier Gonzalo Ocejo-VinyalsDepartment of Immunology, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
Ricardo BlancoImmunopathology Group, Instituto de Investigación Marqués de Valdecilla (IDIVAL), Santander, Spain.
Verónica Pulito-CuetoImmunopathology Group, Instituto de Investigación Marqués de Valdecilla (IDIVAL), Santander, Spain.
Raquel López-MejíasImmunopathology Group, Instituto de Investigación Marqués de Valdecilla (IDIVAL), Santander, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Immunoglobulin A vasculitis (IgAV) is an inflammatory disease mediated by B cells. Nuclear factor kappa B (NF-κB) is essential for B-cell development and maturation and plays a key role in autoimmunity and inflammation. In particular, the NF-κB canonical activation pathway genes Methods: The Results: No statistically significant differences were found in genotype or allele frequencies of Conclusion: Our findings do not support a major role for the

Indexed as

IgA VasculitisImmunoglobulin ANF-KappaB Inhibitor alphaNF-kappa B p50 SubunitVasculitisAdolescentAdultAgedCase-Control StudiesFemaleGenetic Predisposition to DiseaseGenotypeHaplotypesHumansMaleMiddle AgedImmunoglobulin ANF-KappaB Inhibitor alphaNF-kappa B p50 SubunitNFKB1 protein, humanNFKBIA protein, humanbiomarkersimmunoglobulin A vasculitis (IgAV)NF-kappa B (NF-kB)NFKB1NFKBIA

Identifiers

PMID41208975
PMCPMC12592155

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.