Evidence map›Paper›PMID 41209000›Full record

ReviewFrontiers in immunology2025

NETs: a new target for autoimmune disease.

Ran Tang, Jiahua Yin, Zhifang Qin, Min Zhang, Xiaoyi Jia

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ran Tang *School of Pharmacy, Anhui University of Chinese Medicine, Hefei, Anhui, China.
Jiahua Yin *School of Pharmacy, Anhui University of Chinese Medicine, Hefei, Anhui, China.
Zhifang QinSchool of Pharmacy, Anhui University of Chinese Medicine, Hefei, Anhui, China.
Min ZhangDepartment of Rheumatology and Immunology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Xiaoyi JiaSchool of Pharmacy, Anhui University of Chinese Medicine, Hefei, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophil extracellular traps (NETs) are reticular fiber structures released by neutrophils in response to various stimuli. Although NETs have antibacterial defense functions, their excessive formation has been proven to accelerate the progression of autoimmune diseases. Increasing studies have shown that NETs play an important role in the pathogenesis of autoimmune diseases. The pathogenesis of recent advances in autoimmune disease research, with a focus on the role of NETs in the etiology and pathogenesis of these disorders, and summarizes the current treatment strategies targeting NETs, aiming to provide new directions for the treatment of autoimmune diseases.

Indexed as

Autoimmune DiseasesExtracellular TrapsMolecular Targeted TherapyAnimalsHumansNeutrophilsautoimmune diseasemechanismneutrophilneutrophil extracellular trapstargeted therapy

Identifiers

PMID41209000
PMCPMC12589091

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.