ReviewFrontiers in surgery2025
The impact of osteoporosis on arthroscopic rotator cuff repair and postoperative tendon-to-bone healing.
Review in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review explores the impact of osteoporosis on arthroscopic rotator cuff repair and subsequent tendon healing, focusing on challenges such as anchor fixation failure, intraoperative fractures, and limited surgical visibility. It examines how osteoporosis disrupts the tendon healing microenvironment post-surgery through mechanisms involving bone metabolism, growth factors, the immune system, sex hormones, oxidative stress, and adipose infiltration. Effective surgical planning is crucial to mitigate the adverse effects of osteoporosis on rotator cuff repair. This review offers recommendations for optimizing surgical strategies, including anchor selection, placement, and fixation techniques. In addition, it highlights the potential of anti-osteoporotic drugs and biological therapies to improve tendon-to-bone union and enhance clinical outcomes. For cases of inevitable repair failure, remedial strategies are proposed to inform clinical practice. A systematic literature search was conducted in the PubMed, Web of Science, and CNKI databases (2000-2025) using the following keywords: "osteoporosis," "rotator cuff injury," "shoulder arthroscopy," "tendon-to-bone healing," and "retear." The inclusion criteria were as follows: (1) human or animal studies; (2) MRI-confirmed rotator cuff tears; and (3) full-text articles in English or Chinese. The exclusion criteria included case reports (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.