Evidence map›Paper›PMID 41209137›Full record

ReviewReviews in cardiovascular medicine2025

Sepsis-Related Cardiomyopathy: Advances in Diagnosis and Treatment.

Bo Sun, Fenzan Wu, Tianqing Zhang

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bo SunDepartment of Critical Care Medicine, Cixi People Hospital Medical Health Group (Cixi People Hospital), 315300 Cixi, Zhejiang, China.
Fenzan WuDepartment of Critical Care Medicine, Cixi People Hospital Medical Health Group (Cixi People Hospital), 315300 Cixi, Zhejiang, China.
Tianqing ZhangDepartment of Critical Care Medicine, Cixi People Hospital Medical Health Group (Cixi People Hospital), 315300 Cixi, Zhejiang, China.ORCID https://orcid.org/0009-0001-3664-2676

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis-induced cardiomyopathy (SICM) constitutes a critical myocardial impairment that substantially elevates mortality risk in septic patients. The structural and functional changes of SICM are accompanied by metabolic disturbances, including mitochondrial dysfunction and altered myocardial metabolism. Diagnostic advancements feature biomarkers, circulating microRNAs, and imaging tools, such as speckle-tracking echocardiography. Therapies extend from vasopressors to immunomodulators, mitochondrial-targeted antioxidants, and mesenchymal stem cell-based approaches. Despite progress, challenges related to heterogeneity and the need for long-term data persist. Thus, integrated approaches leveraging machine learning and omics are essential for optimizing personalized care and reducing the global burden of SICM.

Indexed as

diagnostic biomarkersmitochondrial dysfunctionmyocardial dysfunctionsepsis-induced cardiomyopathysystemic inflammationtreatment strategies

Identifiers

PMID41209137
PMCPMC12593738

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.