ArticleQuantitative imaging in medicine and surgery2025
Internal carotid artery bifurcation aneurysms are probably formed to decrease the abnormally-enhanced hemodynamic stresses caused by direct flow impaction.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The hemodynamic parameters associated with the presence of internal carotid artery (ICA) bifurcation saccular aneurysms are unknown. This study was conducted to investigate this association using computational fluid dynamic (CFD) analysis of patients' specific three-dimensional (3D) imaging datasets. Methods: Patients with ICA bifurcation saccular aneurysms were retrospectively enrolled, and the 3D angiographic datasets were used for CFD analysis with aneurysm presence and virtual aneurysm removal. Results: A total of 20 patients with ICA bifurcation aneurysms were enrolled, including 15 (75%) female and 5 (25%) male patients aged 26-76 (50.0±13.4) years. Compared with the hemodynamic parameters on the aneurysm dome, the dynamic (median 1.65 Conclusions: ICA bifurcation aneurysm formation is closely associated with significantly decreased hemodynamic stresses, and aneurysm formation occurs to decrease the abnormally-enhanced hemodynamic parameters on the bifurcation apex caused by direct flow impingement.
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