Evidence map›Paper›PMID 41209292›Full record

ArticleJournal of bone oncology2025

Establishment and comprehensive characterization of a subline with highly bone-metastatic propensity derived from the lung adenocarcinoma A549 cell line.

Yujian Xu, Yahan Qin, Wenjun Chai, Ke Xue, Xiaoli Liu, Jing Li, Yue Cao, Lei Sun, Hongyu Pan, Mingxia Yan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bone oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yujian XuCancer Institute, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Yahan QinCancer Institute, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Wenjun ChaiCancer Institute, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Ke XueCancer Institute, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Xiaoli LiuCancer Institute, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Jing LiCancer Institute, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Yue CaoCancer Institute, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Lei SunCancer Institute, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Hongyu PanCancer Institute, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Mingxia YanCancer Institute, Fudan University Shanghai Cancer Center, Shanghai 200032, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone metastasis is a major cause of mortality in lung adenocarcinoma, but the mechanisms remain poorly understood. Here, we established a highly bone-metastatic subline, A549-BM5, from the A549 cell line through five rounds of

Indexed as

Bone MetastasisCell ModelLung AdenocarcinomaTumor Microenviroment

Identifiers

PMID41209292
PMCPMC12595314

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.