Evidence map›Paper›PMID 41209419›Full record

ArticleCurrent research in parasitology & vector-borne diseases2025

Erica Burkman, Lucienne Tritten, Christopher C Evans, Guilherme G Verocai, Caroline Sobotyk, Timothy G Geary, Andrew R Moorhead

Abstract read
In one paragraph

Article in Current research in parasitology & vector-borne diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Erica BurkmanBoehringer Ingelheim Animal Health, Athens, GA, 30601, USA.
Lucienne TrittenMcGill University, Institute of Parasitology, Ste-Anne-de-Bellevue, QC, H9X 3V9, Canada.
Christopher C EvansUniversity of Georgia, College of Veterinary Medicine, Department of Infectious Diseases, Athens, GA, 30602, USA.
Guilherme G VerocaiTexas A&M University, College of Veterinary Medicine & Biomedical Sciences, Department of Veterinary Pathobiology, College Station, TX, 77843, USA.
Caroline SobotykUniversity of Pennsylvania School of Veterinary Medicine, Department of Pathobiology, Philadelphia, PA, 19104, USA.
Timothy G GearyMcGill University, Institute of Parasitology, Ste-Anne-de-Bellevue, QC, H9X 3V9, Canada.
Andrew R MoorheadNorth Carolina State University, Department of Clinical Sciences, College of Veterinary Medicine, Raleigh, NC, 27606, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Host specificity is a critical feature of the survival and proliferation of parasites. In the context of interactions with the host, numerous mechanisms have been identified, particularly in parasitic helminths, that enable manipulation of the host immune system to enhance their own survival. The evolutionary history of these interactions often results in hosts becoming disease-tolerant or asymptomatic, even when burdened with a high number of worms, until a disruption in the host's immune system can trigger a disease state. However, the molecular mechanisms underlying host specificity and the ways in which parasites alter the host's immune system remain largely unexplored. Research conducted on parasite-derived microRNAs (miRNAs) suggests they may play a role in remodeling the host to improve parasite survival and growth, possibly through directed pathology. To further explore this host-parasite relationship, we analyzed plasma of four cats experimentally infected with the filarial nematode

Indexed as

BioinformaticsBrugia malayiCatFelis catusLymphatic filariasismicroRNA

Identifiers

PMID41209419
PMCPMC12593627

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.