Transcriptomic analysis revealed that oar-miR-370-3p was involved in the regulation of wool fineness in Ordos fine-wool sheep.

Cuiling Wu, Gvlnigar Amar, Asma Anwar, Wenna Liu, Sen Tang, Shengchao Ma, Xuefeng Fu

Abstract read

In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

MiR-376c-3p Targets STRBP mRNA to Regulate Cashmere Goat Hair Follicle Stem Cell Proliferation and Multipotency by Inhibiting the Wnt/β-Catenin and BMP Signaling Pathways.Animal genetics · 2026
Article

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5 · Who and what money

Authors and funding

7 authors.

Cuiling WuKey Laboratory of Special Environment Biodiversity Application and Regulation in Xinjiang, International Center for the Collaborative Management of Cross-border Pest in Central Asia, College of Life Sciences, Xinjiang Normal University, Ürümqi, Xinjiang, China.

Gvlnigar AmarKey Laboratory of Special Environment Biodiversity Application and Regulation in Xinjiang, International Center for the Collaborative Management of Cross-border Pest in Central Asia, College of Life Sciences, Xinjiang Normal University, Ürümqi, Xinjiang, China.

Asma AnwarKey Laboratory of Genetic Breeding and Reproduction of Herbivorous Livestock, Ministry of Agriculture and Rural Affairs, Xinjiang Key Laboratory of Animal Biotechnology, Institute of Biotechnology, Xinjiang Academy of Animal Sciences, Ürümqi, Xinjiang, China.

Wenna LiuKey Laboratory of Genetic Breeding and Reproduction of Herbivorous Livestock, Ministry of Agriculture and Rural Affairs, Xinjiang Key Laboratory of Animal Biotechnology, Institute of Biotechnology, Xinjiang Academy of Animal Sciences, Ürümqi, Xinjiang, China.

Sen TangKey Laboratory of Genetic Breeding and Reproduction of Herbivorous Livestock, Ministry of Agriculture and Rural Affairs, Xinjiang Key Laboratory of Animal Biotechnology, Institute of Biotechnology, Xinjiang Academy of Animal Sciences, Ürümqi, Xinjiang, China.

Shengchao MaKey Laboratory of Special Environment Biodiversity Application and Regulation in Xinjiang, International Center for the Collaborative Management of Cross-border Pest in Central Asia, College of Life Sciences, Xinjiang Normal University, Ürümqi, Xinjiang, China.

Xuefeng FuKey Laboratory of Genetic Breeding and Reproduction of Herbivorous Livestock, Ministry of Agriculture and Rural Affairs, Xinjiang Key Laboratory of Animal Biotechnology, Institute of Biotechnology, Xinjiang Academy of Animal Sciences, Ürümqi, Xinjiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNA (miRNA) is a prominent topic in biological research, as it plays a crucial role in regulating various physiological processes. Identifying miRNAs associated with fiber traits enhances our understanding of the complex biological mechanisms involved in hair follicle development and provides potential targets for improving fine-wool sheep breeds. This study focused on 20 Ordos fine-wool sheep and identified miRNA expression profiles in skin tissues through transcriptome sequencing. Key miRNAs related to the diameter of wool fibers were preliminarily screened through cell verification experiments. The results revealed 26 differentially expressed (DE) miRNAs in tissues with varying wool fineness, with 12 DE miRNAs being upregulated and 14 DE miRNAs being downregulated. All DE miRNAs predicted 2,844 target genes. Integrating previous mRNA sequencing data, oar-miR-370-3p has 23 differentially expressed target genes. Following the overexpression of miR-370-3p in fibroblasts, the expression levels of the predicted target genes

Indexed as

fiber diameterfibroblastoar-miR-370-3pOrdos fine-wool sheepwool

Identifiers

PMID41209464

DOI10.3389/fvets.2025.1662962

PMCPMC12593473

What Socratic holds

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