Evidence mapPaperPMID 41209576Full record

ArticleJournal of clinical medicine research2025

Pericardial Fat Tissue as a Predictor of the Severity of Acute Coronavirus Infection COVID-19.

Anna Bragina, Aida Tarzimanova, Yulia Rodionova, Konstantin Osadchiy, Tatiana Ishina, Ivan Medvedev, Lubov Vasileva, Natalia Druzhinina, Karina Umbetova, Olga Belaya and 3 more

Abstract read
In one paragraph

Article in Journal of clinical medicine research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anna BraginaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenovskiy University), Moscow, Russia.ORCID https://orcid.org/0000-0002-2699-1610
Aida TarzimanovaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenovskiy University), Moscow, Russia.ORCID https://orcid.org/0000-0001-9536-8307
Yulia RodionovaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenovskiy University), Moscow, Russia.ORCID https://orcid.org/0000-0003-3461-6703
Konstantin OsadchiyDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenovskiy University), Moscow, Russia.ORCID https://orcid.org/0000-0001-8202-4492
Tatiana IshinaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenovskiy University), Moscow, Russia.ORCID https://orcid.org/0000-0001-7720-0770
Ivan MedvedevDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenovskiy University), Moscow, Russia.ORCID https://orcid.org/0000-0003-4210-2841
Lubov VasilevaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenovskiy University), Moscow, Russia.ORCID https://orcid.org/0000-0001-5730-7837
Natalia DruzhininaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenovskiy University), Moscow, Russia.ORCID https://orcid.org/0000-0001-8397-0210
Karina UmbetovaDepartment of Infectious Diseases, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenovskiy University), Moscow, Russia.ORCID https://orcid.org/0000-0003-0902-9267
Olga BelayaDepartment of Infectious Diseases, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenovskiy University), Moscow, Russia.ORCID https://orcid.org/0000-0002-2722-1335
Maria KutushevaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenovskiy University), Moscow, Russia.ORCID https://orcid.org/0009-0002-3850-4987
Zlata NefedovaDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenovskiy University), Moscow, Russia.ORCID https://orcid.org/0009-0007-0727-3297
Valery PodzolkovDepartment of Internal Medicine No. 2, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenovskiy University), Moscow, Russia.ORCID https://orcid.org/0000-0002-0758-5609

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Coronavirus disease 2019 (COVID-19) and obesity remain pressing global health concerns. Identifying predictors of severe disease is of particular importance. Pericardial fat tissue (PFT) is a known source of metainflammation due to its secretion of adipocytokines and inflammatory mediators. Moreover, cytokine storm plays a major role in COVID-19-related mortality. This study aimed to investigate the association between preexisting PFT volume and inflammatory markers in patients with COVID-19. Methods: The study included 290 hospitalized patients with confirmed COVID-19 infection. Based on PFT volume (above or below 3.45 cm Results: Significant intergroup differences were observed in the PO group for the following variables: male sex (P < 0.001), body mass index (BMI) (P < 0.001), obesity (P < 0.001), and history of diabetes mellitus (P = 0.003). No significant differences were found in lung computed tomography (CT) severity scores. However, patients with PO showed significantly lower oxygen saturation (SpO Conclusions: Our data suggest that a PFT volume greater than 3.45 cm

Indexed as

COVID-19InflammationObesityPericardial fat tissueSARS-CoV-2 infection

Identifiers

PMID41209576
PMCPMC12591241

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.