Evidence map›Paper›PMID 41209733›Full record

ArticleFrontiers in microbiology2025

Postbiotic supplementation promotes gut barrier integrity and immune balance in cats via microbiota modulation.

Weiwei Wang, Chengyi Miao, Qianqian Chen, Longjiao Wang, Xiaohan Chang, Lili Zhao, Wenjing Ma, Shanyu Lei, Mengyao Ma, Yuqiang Zhang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Weiwei Wang *Food Laboratory of Zhongyuan, College of Food Science and Technology, Henan University of Technology, Zhengzhou, Henan, China.
Chengyi Miao *Food Laboratory of Zhongyuan, College of Food Science and Technology, Henan University of Technology, Zhengzhou, Henan, China.
Qianqian ChenFood Laboratory of Zhongyuan, College of Food Science and Technology, Henan University of Technology, Zhengzhou, Henan, China.
Longjiao WangHenan Zhiyuan Henuo Technology Co., Ltd., Luohe, China.
Xiaohan ChangFood Laboratory of Zhongyuan, College of Food Science and Technology, Henan University of Technology, Zhengzhou, Henan, China.
Lili ZhaoFood Laboratory of Zhongyuan, College of Food Science and Technology, Henan University of Technology, Zhengzhou, Henan, China.
Wenjing MaFood Laboratory of Zhongyuan, College of Food Science and Technology, Henan University of Technology, Zhengzhou, Henan, China.
Shanyu LeiFood Laboratory of Zhongyuan, College of Food Science and Technology, Henan University of Technology, Zhengzhou, Henan, China.
Mengyao MaFood Laboratory of Zhongyuan, College of Food Science and Technology, Henan University of Technology, Zhengzhou, Henan, China.
Yuqiang ZhangFood Laboratory of Zhongyuan, College of Food Science and Technology, Henan University of Technology, Zhengzhou, Henan, China.
Shuxing ChenFood Laboratory of Zhongyuan, College of Food Science and Technology, Henan University of Technology, Zhengzhou, Henan, China.
Lishui ChenFood Laboratory of Zhongyuan, College of Food Science and Technology, Henan University of Technology, Zhengzhou, Henan, China.
Ran WangKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Shaoyang GeKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Wei XiongFood Laboratory of Zhongyuan, College of Food Science and Technology, Henan University of Technology, Zhengzhou, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Gastrointestinal disorders are common in cats and are closely linked to the gut microbiota, which supports immune function, metabolic balance, and barrier integrity. Although probiotics are beneficial, they can be unstable in pet foods. Postbiotics offer a safer and more stable alternative. Methods: A postbiotic derived from Results: Postbiotic supplementation improved fur condition and enhanced gut barrier integrity, as indicated by reduced levels of permeability markers such as diamine oxidase (DAO) and lipopolysaccharide (LPS). It also promoted immune function by increasing serum immunoglobulin G and anti-inflammatory cytokines IL-10 and IL-4. In addition, the intervention enriched beneficial bacteria such as Discussion: These findings support the use of postbiotics as a safe and effective nutritional approach to help maintain gastrointestinal and immune health in cats.

Indexed as

feline healthgut microbiotaimmune modulationintestinal barrierpostbiotics

Identifiers

PMID41209733
PMCPMC12592049

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.