An Unusual Case of Nonneutropenic Fever Associated With Myelodysplasia and Sweet's Syndrome.

Priscila Lopez, Enoch J Abbey, Boakye-Yiadom Adomako, Meena Ahluwalia, Karen Simon

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In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Priscila LopezDepartment of Internal Medicine and Infectious Disease, Harlem Hospital Center, Columbia University, New York, USA.

Enoch J AbbeyDepartment of Internal Medicine, Harlem Hospital Center, Columbia University, New York, USA.

Boakye-Yiadom AdomakoDepartment of Internal Medicine, Harlem Hospital Center, Columbia University, New York, USA.

Meena AhluwaliaDepartment of Oncology, Harlem Hospital Center, Columbia University, New York, USA.

Karen SimonDepartment of Internal Medicine, Harlem Hospital Center, Columbia University, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sweet's syndrome (SS) is a rare paraneoplastic condition characterized by skin lesions, fever, and leukocytosis. It is typically associated with hematological malignancies but is also linked to solid tumors, medications, and inflammatory diseases. The onset of SS can precede or coincide with the discovery of an undiagnosed cancer. Here, we present the case of a 72-year-old woman with neutropenic fever and an incidental nodule in the right breast. Skin biopsy revealed a neutrophilic infiltrate within the deeper dermis and likely subcutis, which is diagnostic for SS. Successful treatment with systemic steroids was administered, while the concurrent diagnosis of myelodysplastic syndrome led to the initiation of decitabine therapy following a bone marrow biopsy.

Indexed as

leukocytoclasiamyelodysplastic syndromeneutropenic feversweet's syndromethrombotic thrombocytopenic purpura

Identifiers

PMID41209929

DOI10.7759/cureus.94166

PMCPMC12595284

What Socratic holds

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.