ArticleFrontiers in cardiovascular medicine2025
Ultrasonic and clinical risk factors of solitary Plaque-RADS-2 carotid plaque for predicting anterior circulation ischemic stroke.
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Plaque-RADS-2 carotid plaque is regarded as a low risk for attribution of cerebrovascular events. Nevertheless, in individuals with carotid plaque, the risk of ischemic stroke poses a continuous threat to both health and quality of life. This study aimed to investigate risk predictors of anterior circulation ischemic stroke (ACIS) in patients with solitary Plaque-RADS-2 carotid plaque. Methods: Medical records of 1,961 patients were collected at our hospital from January to December 2022. Patients with solitary Plaque-RADS-2 carotid plaque were divided into ACIS and non-ACIS groups based on brain CT/MRI results. Ultrasonic and clinical characteristics were assessed by univariate and multivariate analysis. Results: A total of 134 patients with solitary Plaque-RADS-2 carotid plaque were enrolled in this study. Systolic blood pressure (SBP) >141.5 mmHg, glycosylated hemoglobin (HbA1c) > 7.05%, triglyceride glucose (TyG) index > 7.18, and mainly hypoechoic significantly were predictive factors for ACIS. The prediction equation was logit ( Conclusion: This study demonstrated that SBP > 141.5 mmHg, HbA1c > 7.05%, TyG index > 7.18, and mainly hypoechoic were independent predictors of ACIS in patients with solitary Plaque-RADS-2 carotid plaque. Significant attention should be given to these risk factors to improve the management of solitary Plaque-RADS-2 carotid plaque.
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