Evidence map›Paper›PMID 41210984›Full record

ArticleiScience2025

TAOK2 controls synaptic plasticity and anxiety via ERK and calcium signaling.

Wenbo Ma, Inanna Warnhoff, Marius Stephan, Xiao Ma, Kerstin Dehne, Paul Volkmann, Nirmal Kannaiyan, Ben Brankatschk, Niels Jensen, Moritz J Rossner and 2 more

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wenbo MaResearch Group Cell Signalling, Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336 Munich, Germany.
Inanna WarnhoffResearch Group Neurophysiology of Psychiatric Disease, Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336 Munich, Germany.
Marius StephanSystasy Bioscience GmbH, Fraunhoferstr. 8, 82152 Planegg, Germany.
Xiao MaResearch Group Cell Signalling, Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336 Munich, Germany.
Kerstin DehneMolecular Neurobiology, Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336 Munich, Germany.
Paul VolkmannMolecular Neurobiology, Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336 Munich, Germany.
Nirmal KannaiyanSystasy Bioscience GmbH, Fraunhoferstr. 8, 82152 Planegg, Germany.
Ben BrankatschkSystasy Bioscience GmbH, Fraunhoferstr. 8, 82152 Planegg, Germany.
Niels JensenSystasy Bioscience GmbH, Fraunhoferstr. 8, 82152 Planegg, Germany.
Moritz J RossnerSystasy Bioscience GmbH, Fraunhoferstr. 8, 82152 Planegg, Germany.
Volker ScheussResearch Group Neurophysiology of Psychiatric Disease, Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336 Munich, Germany.
Michael C WehrResearch Group Cell Signalling, Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Nussbaumstr. 7, 80336 Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The kinase thousand and one amino acid kinase 2 (TAOK2) regulates dendritic architecture and synaptic plasticity and is implicated in neurodevelopmental and neuropsychiatric disorders, including autism and schizophrenia. Here, we investigated TAOK2 function by creating an

Indexed as

Cellular neuroscienceMolecular neuroscienceTranscriptomics

Identifiers

PMID41210984
PMCPMC12590003

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.