ReviewJournal of multidisciplinary healthcare2025
Global Research Trends in Sepsis-Associated Coagulopathy: A Web of Science-Based Bibliometric Analysis (2000-2024).
Review in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Biomarkers and clinical factors associated with sepsis-induced coagulopathy: A systematic review and meta-analysis.Science progress · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Sepsis-induced coagulopathy (SIC) is a critical determinant of organ dysfunction and mortality in patients with sepsis. While research in this field is rapidly expanding, a comprehensive, quantitative analysis of its knowledge landscape is lacking. This study aims to conduct a bibliometric analysis to delineate the global research status, identify thematic hotspots, and reveal emerging frontiers in the field of SIC from 2000 to 2024. Methods: We retrieved publications related to SIC from the Web of Science Core Collection (WoSCC), with the final search conducted on May 27, 2025. Only original English-language 'Articles' were included. Bibliometric analysis and knowledge mapping were performed using VOSviewer (v1.6.18) and CiteSpace (v6.2.R6) to analyze countries, authors, journals, co-cited references, and keywords. Results: A total of 1715 publications were included. The annual publication volume showed an exponential growth trend, particularly after 2020. The United States was the leading country in publication output (471 articles, 27.5%), and Critical Care Medicine was the most productive journal (106 articles). The PROWESS trial published by Bernard GR et al (2001) was the most co-cited foundational document with 4,188 co-citations. Keyword analysis identified four major research clusters: (1) Pathophysiological Mechanisms and Endothelial Injury, (2) Diagnostic Biomarkers and Prognostic Assessment, (3) Anticoagulant Therapy and Clinical Management, and (4) Immunothrombosis and Neutrophil Extracellular Traps (NETs). Conclusion: Over the past two decades, research on SIC has evolved from exploring fundamental coagulation pathways to investigating the intricate mechanisms of immunothrombosis. Current research hotspots focus on endothelial injury, NETs, and the development of precise diagnostic and therapeutic strategies. This analysis provides a quantitative map of the knowledge structure and emerging trends in the SIC field, offering a valuable reference for future research priorities.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.