Evidence map›Paper›PMID 41211170›Full record

ArticleFood science & nutrition2025

Immunomodulatory Effects of Multi-Strain Probiotic Capsules for Psoriatic Arthritis: A Pilot Double-Blind Randomized Controlled Trial.

Ahmed Hussein Hasan Alshihmani, Hanieh Kolahdooz, Mahmoud Mahmoudi, Zahra Rezaieyazdi, Ramiar Kamal Kheder, Nafiseh Sadat Tabasi, Afsane Fadaee, Seyed-Alireza Esmaeili

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ahmed Hussein Hasan AlshihmaniImmunology Research Center Mashhad University of Medical Sciences Mashhad Iran.
Hanieh KolahdoozImmunology Research Center Mashhad University of Medical Sciences Mashhad Iran.
Mahmoud MahmoudiImmunology Research Center Mashhad University of Medical Sciences Mashhad Iran.
Zahra RezaieyazdiRheumatic Diseases Research Center Mashhad University of Medical Sciences Mashhad Iran.
Ramiar Kamal KhederMedical Laboratory Science Department, College of Science University of Raparin Rania Iraq.
Nafiseh Sadat TabasiImmunology Research Center Mashhad University of Medical Sciences Mashhad Iran.
Afsane FadaeeImmunology Research Center Mashhad University of Medical Sciences Mashhad Iran.
Seyed-Alireza EsmaeiliImmunology Research Center Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0002-9371-4170

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriatic arthritis (PsA) is characterized by joint inflammation and is frequently associated with psoriasis. Gut dysbiosis has been implicated in PsA pathogenesis, raising interest in probiotics as potential immunomodulatory agents. In a pilot, double-blind, randomized, placebo-controlled trial, 14 adults aged 18-60 years with mild-to-moderate psoriatic arthritis (PsA; Disease Activity in Psoriatic Arthritis [DAPSA] < 28) were randomized to receive either probiotic capsules or placebo daily for 12 weeks. The probiotic group received a multi-strain cocktail with a total concentration of 1 × 10

Indexed as

B cellIFNγIL‐10IL‐4probioticspsoriasis arthritisTGFβTh1

Identifiers

PMID41211170
PMCPMC12588955

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.