Observational studyPeerJ2025
Cognitive domain-specific impairments and associated risk factors in type 2 diabetes mellitus: a cross-sectional observational study based on neuropsychological assessment from Xiamen, China.
Observational study in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Neurovascular Actions of Dipeptidyl Peptidase-4 Inhibitors and Their Implications for Cognitive Dysfunction in Type 2 Diabetes Mellitus.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026Review
- The effects of prediabetes and type 2 diabetes mellitus on cognitive status, physical function, and fatigue in older adults: a case-control study.Irish journal of medical science · 2026Article
- The performance of a novel, diabetes-specific cognitive screening tool against the MoCA in older adults with type 2 diabetes.BMC geriatrics · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Type 2 diabetes mellitus (T2DM) is associated with an increased risk of cognitive impairment, yet limited research has been conducted in subtropical regions of China. Objective: To examine the characteristics of cognitive impairment and identify the potential risk factors in patients with T2DM in Xiamen. Methods: This cross-sectional observational study included 84 patients with T2DM from Zhongshan Hospital Xiamen University. Patients were grouped based on their Montreal Cognitive Assessment (MoCA) scores into a cognitively impaired group (T2DM-CI group, Results: Among the 52 patients in the T2DM-CI group, the most commonly affected cognitive domains were executive function (82.7%), language (75.0%), memory (61.5%), and attention (48.1%), with 59.6% exhibiting impairments in three or more domains. Compared with the T2DM-NCI group, the T2DM-CI group showed poorer performance in most MoCA subdomains-including visuospatial/executive function, language, delayed recall, abstraction, and orientation-as well as in individual cognitive domain tests (all Conclusion: Cognitive impairment in T2DM affects multiple domains, with executive dysfunction most prominent. Age and elevated lipoprotein(a) may increase risk. Routine cognitive screening is warranted, particularly in older patients and those with vascular risk factors.
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Registered trials
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