Article in Journal of enzyme inhibition and medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
17 authors.
Silvia Alejandra Meza-IretaFacultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Puebla, PUE, México.
Laura L Romero-HernándezFacultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Puebla, PUE, México.ORCID 0000-0001-9658-532X
Paloma BeginesDepartamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, Seville, Spain.ORCID 0000-0001-5188-2005
Simone GiouvannuziNEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, Florence, Italy.
Adrián PuertaBioLab, Instituto Universitario de Bio-Orgánica "Antonio González" (IUBO-AG), La Laguna, Spain.ORCID 0000-0002-7975-1960
Aday González-BakkerBioLab, Instituto Universitario de Bio-Orgánica "Antonio González" (IUBO-AG), La Laguna, Spain.ORCID 0000-0002-9792-5194
Amador Romero-FrancoDepartamento de Genética, Facultad de Biología, Universidad de Sevilla, Sevilla, Spain.ORCID 0000-0003-3212-1643
Pablo HuertasDepartamento de Genética, Facultad de Biología, Universidad de Sevilla, Sevilla, Spain.ORCID 0000-0002-1756-4449
Alessio NocentiniNEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, Florence, Italy.ORCID 0000-0003-3342-702X
José Luis Vega-BáezFacultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Puebla, PUE, México.
Sara Montiel-SmithFacultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Puebla, PUE, México.ORCID 0000-0002-3080-9252
José G Fernández-BolañosDepartamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, Seville, Spain.ORCID 0000-0003-1499-0650
Maikel Castellano-PozoDepartamento de Genética, Facultad de Biología, Universidad de Sevilla, Sevilla, Spain.ORCID 0000-0003-4134-9025
José M PadrónBioLab, Instituto Universitario de Bio-Orgánica "Antonio González" (IUBO-AG), La Laguna, Spain.ORCID 0000-0001-6268-6552
Claudiu T SupuranNEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, Florence, Italy.ORCID 0000-0003-4262-0323
Penélope Merino-MontielFacultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Puebla, PUE, México.ORCID 0000-0003-1376-9671
Óscar LópezDepartamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, Seville, Spain.ORCID 0000-0003-2896-6993
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
We synthesised coumarin-based derivatives bearing thio- and selenocyanates to selectively inhibit tumour-associated carbonic anhydrases (CAs) IX and XII and to exert antiproliferative effects on tumour cells. Structural variations included chalcogen atom type (S, Se), substitutions at C-3/C-4, and tether length at C-7 of the coumarin core. Thiocyanates
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Harnessing coumarin-thio(seleno)cyanate conjugates: potent · full record | Socratic