ArticleDiscover oncology2025
A comprehensive bibliometric and visual analysis of tumor-associated macrophages in hepatocellular carcinoma.
Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundHepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality and primarily develops due to chronic liver diseases. Tumor-associated macrophages (TAMs) play an essential role in HCC progression. Understanding the role of TAMs in HCC is crucial to advancing research and treatment strategies.
methodsWe conducted a comprehensive search in the Web of Science Core Collection from 1990 to 2024, identifying a total of 4,111 relevant publications. Advanced data visualization tools, including VOSviewer and CiteSpace, were utilized to map research trends and collaboration networks in this field.
resultsOur findings revealed a growing focus on key aspects such as macrophage dynamics, immune infiltration, and therapeutic targeting, underscoring the critical role that TAMs play in HCC progression and treatment. We observed significant contributions from research institutions in both China and the United States, with emerging hotspots centered around immunotherapy and exosome interactions.
conclusionThis comprehensive bibliometric analysis has highlighted the increasing importance of TAMs in HCC research and identified promising future research directions aimed at enhancing therapeutic strategies for patients afflicted with this disease.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.