Evidence map›Paper›PMID 41212652›Full record

ArticleJournal of Alzheimer's disease : JAD2026

Evaluation of a panel of plasma biomarkers for Alzheimer's disease in a diverse research cohort.

Kelly N DuBois, Subhamoy Pal, Jonathan M Reader, Brianna Jackman, Matthew D Perkins, Nahla Khobeir, Kelly M Bakulski, Judith Heidebrink, Benjamin M Hampstead, David G Morgan and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kelly N DuBoisDepartment of Translational Neuroscience, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA.ORCID 0000-0002-1349-1983
Subhamoy PalMichigan Alzheimer's Disease Research Center, University of Michigan, Ann Arbor, MI, USA.
Jonathan M ReaderMichigan Alzheimer's Disease Research Center, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-3245-9196
Brianna JackmanDepartment of Translational Neuroscience, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA.
Matthew D PerkinsMichigan Alzheimer's Disease Research Center, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0001-7715-0638
Nahla KhobeirMichigan Alzheimer's Disease Research Center, University of Michigan, Ann Arbor, MI, USA.
Kelly M BakulskiMichigan Alzheimer's Disease Research Center, University of Michigan, Ann Arbor, MI, USA.
Judith HeidebrinkMichigan Alzheimer's Disease Research Center, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0003-0319-9257
Benjamin M HampsteadMichigan Alzheimer's Disease Research Center, University of Michigan, Ann Arbor, MI, USA.
David G MorganDepartment of Translational Neuroscience, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA.ORCID 0000-0003-1224-7476
Nicholas M KanaanDepartment of Translational Neuroscience, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA.ORCID 0000-0002-4362-2593

Funding

Research Education ComponentP30AG072931 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Henry L Paulson · 2021 to 2026
$26.5M
NIA NIH HHS P30 AG072931
6 · The paper itself

Abstract

BackgroundPlasma biomarkers show significant promise for Alzheimer's disease (AD) diagnostics and risk prediction, however, much less is known about how these assays perform in a diverse research cohort of older adults.ObjectiveTo compare plasma biomarkers with clinical diagnoses and assess variability by demographic factors in a diverse research cohort.MethodsAmong 331 University of Michigan Memory and Aging Project (UM-MAP) participants, plasma biomarkers (pTau-217, pTau-181, GFAP, NfL, Aβ

Indexed as

Alzheimer DiseaseBiomarkersAgedAged, 80 and overAmyloid beta-PeptidesCognitive DysfunctionCohort StudiesFemaleHumansMaleMiddle AgedNeuropsychological Teststau ProteinsAmyloid beta-PeptidesBiomarkerstau ProteinsAlzheimer's diseaseamyloid-βblood biomarkerscognitive dysfunctiondementiaGFAPmild cognitive impairmenttau

Identifiers

PMID41212652
PMCPMC12643100

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.