ArticleMolecular pharmaceutics2025
Primary Small Intestinal Epithelia Are Physiological Alternatives to the Caco-2 Lymphatic Transport Model.
Ian M Smith, Oljora Rezhdo, Meihui Pan, Mitesh Patel, Nichola Smith, David T Breault, Ryan M Pelis, Rebecca L Carrier
Abstract read
In one paragraphArticle in Molecular pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
8 authors.
Ian M SmithDepartment of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02110, United States.ORCID 0000-0001-8483-2311 Oljora RezhdoDepartment of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02110, United States.
Meihui PanNovartis Institutes for BioMedical Research, Inc., 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Mitesh PatelNovartis Institutes for BioMedical Research, Inc., 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Nichola SmithNovartis Institutes for BioMedical Research, Inc., 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
David T BreaultDivision of Endocrinology, Boston Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, United States.
Ryan M PelisNovartis Institutes for BioMedical Research, Inc., 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Rebecca L CarrierDepartment of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02110, United States.ORCID 0000-0003-3002-7098 Funding
STRUCTURE-FUNCTION RELATIONSHIPS IN THE ALIMENTARY TRACTP30DK034854 · NIDDK · HARVARD UNIVERSITY (MEDICAL SCHOOL) · 1986 to 2025
$7.9MImpact of lipids and food on oral compound absorption: mechanistic studies and modelingR35GM153324 · NORTHEASTERN UNIVERSITY · 2025 to 2025
$400kNIDDK NIH HHS P30 DK034854NIGMS NIH HHS R35 GM153324
6 · The paper itselfAbstract
Indexed as
Intestinal MucosaIntestine, SmallAlanineAnimalsApolipoprotein B-48Biological TransportCaco-2 CellsChylomicronsDuodenumGlyceridesHumansIleumMiceMicellesOleic AcidPhenanthrenesAlanineApolipoprotein B-48ChylomicronsGlycerideshalofantrineMicellesmonooleinOleic AcidPhenanthrenes2-MG re-esterificationapolipoprotein BCaco-2chylomicron transporthalofantrineintestinal organoidslymphatic drug deliverynavitoclaxNew Approach Methodologyoral absorption model
Identifiers
PMID41212758
PMCPMC13384525
What Socratic holds
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