ReviewAnnual review of physiology2026
Brain Nutrient Sensing: A Unifying Framework.
Review in Annual review of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Peptide Hormones in Appetite Regulation: A Complex Network.Pharmaceuticals (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Whole-body nutrient homeostasis is critical for healthy growth, successful reproduction, and survival. We propose a conceptual framework emphasizing the role of brain nutrient sensing in mediating adaptive responses for the maintenance of nutrient homeostasis. Specialized brain nutrient-sensing cells monitor nutrients and meal-related signals, provide feedback responses to maintain internal nutrient availability, and adapt physiological functions according to environmental nutrient fluctuations. Maladaptive functioning of these pathways may underlie multiple pathophysiological conditions, including cardiometabolic and neurodegenerative diseases. By examining recent advances, this review highlights the importance of brain nutrient sensing in adaptive systemic physiology and behavior, exploring the potential of these neural pathways as therapeutic targets extending beyond obesity management. Ultimately, the goal of this review is to synthesize current evidence into a coherent framework that guides new mechanistic hypotheses, facilitating deeper investigation into how brain nutrient sensing influences health and contributes to disease pathogenesis.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.