Evidence map›Paper›PMID 41214060›Full record

ArticleScientific reports2025

Identification of T cell stress response state (T

Xingfeng Zhuo, Xue Xing, Kai Xing, Li Zhang, Yong Wang, Yao Yao, Xia Li, Qian Li, Nan Chen, Chunxia Chen and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xingfeng Zhuo *Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China.
Xue Xing *Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China.
Kai XingJinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China.
Li ZhangSchool of Early-Childhood Education, NanJing XiaoZhuang University, Nanjing, 210000, China.
Yong WangJinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China.
Yao YaoJinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China.
Xia LiJinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China.
Qian LiJinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China.
Nan ChenJinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China.
Chunxia ChenJinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China.
Xiaoling YuJinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China. 703232237@qq.com.
Juanjuan PengJinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China. 2797790941@qq.com.
Lei ZhangJinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China. hellokirk233@126.com.

Funding

Jiangsu Provincial Natural Science Foundation General Program "Study on the Spatiotemporal Information Processing Mechanisms of the Frontoparietal Network in Transitive Inference Among 5-6-Year-Old Preschool Children" BK20221181
6 · The paper itself

Abstract

The malignant transformation risk and high misdiagnosis rate of discoid lupus erythematosus (DLE) render it an urgent necessity to deeply explore its pathogenesis and biomarkers. This research, through the combined analysis of transcriptome data and single-cell sequencing data, commencing from the highly infiltrated T cells in DLE and the significant inflammation and cytokine correlation manifested by T cells, undertakes re-clustering analysis of T cells and identifies the stress response state T cells (T

Indexed as

Lupus Erythematosus, DiscoidStress, PhysiologicalT-LymphocytesChemokine CXCL13Gene Expression ProfilingGene Expression RegulationHumansSingle-Cell AnalysisTranscriptomeChemokine CXCL13CXCL13 protein, human

Identifiers

PMID41214060
PMCPMC12603320

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.