Evidence map›Paper›PMID 41214355›Full record

SynthesisSurgical endoscopy2026

Hepatic adenoma regression after bariatric surgery: a case series and systematic review.

Ian C Garbarine, Amanda K Walsh, Timothy M Pawlik, Sabrena F Noria, Jordan M Cloyd

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Nonoperative Management of Hepatic Adenomas: A Review.Journal of gastrointestinal cancer · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ian C Garbarine *Department of Surgery, The Ohio State University Wexner Medical Center, 410 W 10 Ave, N943 Doan Hall, Columbus, OH, 43210, USA.
Amanda K Walsh *Department of Surgery, The Ohio State University Wexner Medical Center, 410 W 10 Ave, N943 Doan Hall, Columbus, OH, 43210, USA.
Timothy M PawlikDivision of Surgical Oncology, The Ohio State University Wexner Medical Center, 410 W 10th Ave, N907 Doan Hall, Columbus, OH, 43210, USA.
Sabrena F NoriaDivision of General and Gastrointestinal Surgery, Department of Surgery, 410 W 10th Ave N718 Doan Hall, Columbus, OH, 43210, USA.
Jordan M CloydDivision of Surgical Oncology, The Ohio State University Wexner Medical Center, 410 W 10th Ave, N907 Doan Hall, Columbus, OH, 43210, USA. jordan.cloyd@osumc.edu.ORCID http://orcid.org/0000-0002-2373-8433

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatic adenomas (HA) are benign neoplasms of the liver that have small risks of hemorrhage and malignant transformation. While the association between obesity and the development of HAs is increasingly recognized, the impact of bariatric surgery on HA regression is poorly understood.

methodsAll patients with a pre-operative diagnosis of HA who underwent primary bariatric surgery (sleeve gastrectomy or Roux-en-Y gastric bypass) at a single quaternary academic medical center from 2012 to 2024 were retrospectively queried and combined with all previously reported cases obtained via a systematic review of the literature. Patient clinical characteristics, including pre-operative and post-operative body mass index (BMI) and HA size, were extracted. Kendall's Tau-b correlation and fractional probit regression were used to assess the relationship between weight loss and HA size change.

resultsThe institutional review identified three patients, and the systematic review yielded five studies totaling seven patients. In the combined cohort (mean age 34.8 years), the average pre-operative BMI was 44.48 kg/m

conclusionsIn this combined case series and systematic review of the literature, bariatric surgery was associated with high rates of HA regression. Given the additional benefits of weight loss from bariatric surgery and the significant morbidity associated with liver resection, bariatric surgery could be considered as an initial management option for obese patients with HA.

Indexed as

AdenomaBariatric SurgeryLiver NeoplasmsObesity, MorbidAdultBody Mass IndexFemaleHumansMaleMiddle AgedRetrospective StudiesWeight LossBariatric surgeryGastric sleeveHAHepatic adenomaRegressionRoux-en-Y gastric bypass

Identifiers

PMID41214355
PMCPMC12881035

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.