Evidence map›Paper›PMID 41214509›Full record

Observational studyBMC emergency medicine2025

Clinical utility of Thromboelastography in patients with COVID-19: a prospective observational study.

A Deepak Sai, Ravindra Prithvishree, K Nagesh Savan, Mohan Ganesh, Gupta Nitin, Kishore Asish, S Nisarg, Chaudhuri Souvik, Paonam Bemma

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

A Deepak SaiDepartment of Emergency Medicine, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Ravindra PrithvishreeDepartment of Emergency Medicine, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
K Nagesh SavanDepartment of Anesthesiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Mohan GaneshDepartment of Immunohematology and Blood Transfusion, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India. ganesh.mohan@manipal.edu.
Gupta NitinDepartment of Infectious Diseases, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Kishore AsishDepartment of Emergency Medicine, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
S NisargDepartment of Emergency Medicine, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Chaudhuri SouvikDepartment of Critical Care Medicine, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Paonam BemmaDepartment of Immunohematology and Blood Transfusion, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCoronavirus disease (COVID-19) has been associated with thromboembolic and bleeding complications. Our study aims to understand the utility of early Thromboelastography (TEG) in the emergency department as a point-of-care test in predicting clinical outcomes. MATERIALS AND METHODOLOGY: A prospective observational study was conducted in the emergency medicine department (ED) during June 2021- May 2022 with inclusion criteria of all patients above 18 years who arrived at the ED and had a positive COVID-19 RT PCR test. Hematological investigation, including TEG, was sent. Patients were followed up for 28-day mortality, thrombotic and bleeding complications.

resultsA total of 166 patients were enrolled in the study. 46% of patients had critical COVID-19. TEG was abnormal in 45% of patients. Hypercoagulability was seen in 32% of patients. 28-day mortality in our study population was 32.3%. The most common thrombotic complications were stroke (4.2%), myocardial infarction (3.6%), pulmonary embolism (1.2%), and DVT (0.6%). Logistic regression analysis showed that patients who had hypocoagulable TEG had a higher 28-day mortality.

conclusionCOVID-associated coagulopathy can be associated with both thrombotic (venous and arterial) and bleeding complications. Hypocoagulability on initial TEG has a 7.49 times increased risk of mortality. Hypocoagulable TEG indicates an early predictor for mortality. Early TEG can be an essential tool in managing COVID-associated coagulopathy.

Indexed as

COVID-19ThrombelastographyAdultAgedEmergency Service, HospitalFemaleHumansMaleMiddle AgedProspective StudiesThrombosisCOVID-19COVID-associated coagulopathyHyper coagulopathyTEGThrombosis

Identifiers

PMID41214509
PMCPMC12604182

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.