Evidence map›Paper›PMID 41214535›Full record

ArticleBMC microbiology2025

Transport stress alters serum biochemistry and gut microbiota in Tibetan sheep (ovis aries): a 30-day recovery assessment.

Ru Wang, Mingming Wang, Jiahao Wang, Penghui Wang, Jingyu Ou, Wenhui Tang, Ge Sun, Qiangjun Wang, Xiao Cheng, Yafeng Huang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ru Wang *College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Mingming Wang *College of Animal Science and Technology, Southwest University, Chongqing, 400715, China.
Jiahao WangCollege of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Penghui WangCollege of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Jingyu OuCollege of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Wenhui TangCollege of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Ge SunCollege of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Qiangjun WangCollege of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Xiao ChengCollege of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Yafeng HuangCollege of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Jiahong ChenCollege of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Zijun ZhangCollege of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China.
Chunhuan RenCollege of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China. renchunhuan@ahau.edu.cn.

Funding

The National Modern Meat Sheep Industry Technology System CARS-38The Science and Technology Program of Qinghai Province 2022-NK-134The Scientific Research Project of Anhui Higher Education Institutions 2023AH050981
6 · The paper itself

Abstract

backgroundTransport stress poses a major challenge to the livestock industry. Studies have shown that transportation stress can cause depression, elevated body temperature and dysbiosis of intestinal microbiota in meat goats, and in severe cases, even lead to death of the animals, which in turn affects the economic efficiency of the farming industry. However, the changes in blood biochemical indicators and flora of Tibetan sheep throughout the receiving period after long-distance transport remain unclear.

methodsIn this study, six 7-month-old Tibetan sheep with similar body weights were selected for a 30-d transport trial, and blood and faecal samples were collected for blood biochemical indices and 16 S microbiome sequencing before transport (BT), and on day 1 (AT 1), day 16 (AT 16), and day 30 (AT 30) after the end of the transport, respectively.

resultAnd a number of blood biochemical indices (creatine kinase (CK), lactate dehydrogenase (LDH), alkaline phosphatase (ALP), aspartate aminotransferase (AST), cortisol (COR), and adrenocorticotropic hormone (ACTH)) were significantly elevated (P < 0.05). Combined analysis of physiological and biochemical indices with 16 S rDNA sequencing showed that Turicibacter, Romboutsia and Clostridium_sensu_stricto_1 were positively correlated with LDH, ALP, CK, AST, and ACTH, while Prevotellaceae_UCG_004 was negatively correlated. Furthermore, the observed recovery trends in vital signs after AT 16 suggest that Tibetan sheep may be able to adapt to the new environment within one month post-transport. The present study illustrated the effects of transport without measures on the vital signs, serum biochemical indicators and faecal microorganisms of Tibetan sheep throughout the receiving period, which is of great significance in guiding the transport of Tibetan sheep and solving the damage caused by transport stress on the economic benefits of the farming industry.

Indexed as

Gastrointestinal MicrobiomeStress, PhysiologicalTransportationAdrenocorticotropic HormoneAnimalsBacteriaFecesHydrocortisoneRNA, Ribosomal, 16SSheepTibetAdrenocorticotropic HormoneHydrocortisoneRNA, Ribosomal, 16SFecal microorganismsSerum biochemical indexTibetan sheepTransport stressVital signs

Identifiers

PMID41214535
PMCPMC12604201

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.