ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2025
Factors Associated with Blood Glucose Fluctuations in Patients with Type 2 Diabetes: A Retrospective Observational Study Using Continuous Glucose Monitoring.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the factors associated with glucose fluctuations in patients with type 2 diabetes mellitus (T2DM) using continuous glucose monitoring (CGM). Methods: This retrospective observational study included 252 patients with T2DM who underwent CGM during hospitalization. Participants were stratified into two groups based on their coefficient of variation (CV) of glucose: the high-CV group (CV ≥ 33%, n=53) and the low-CV group (CV < 33%, n=199). Glucose fluctuation indices were calculated from CGM data. All patients underwent 3-day CGM during hospitalization. General clinical data and biochemical indicators were collected. Statistical analyses included Results: Significant differences were observed between the two groups in terms of disease duration, BMI, triglycerides, and C-peptide levels ( Conclusion: This study suggests that patients with longer disease duration, lower BMI, and poorer pancreatic function have higher odds of significant glucose fluctuations. Enhanced monitoring of glucose fluctuations and education on potential risks are recommended for these subgroups to improve self-management abilities.
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