ArticleTranslational pediatrics2025
Global burden, inequalities, frontier dynamics, and risk factors of sudden infant death syndrome, 1990-2021: a systematic analysis from the global burden of disease study 2021.
Article in Translational pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Sudden infant death syndrome (SIDS) remains a critical global public health threat. This study comprehensively assessed the global burden, inequalities, frontier progress, and risk factors of SIDS from 1990 to 2021. Methods: Using data from the Global Burden of Disease (GBD) 2021 study, we performed a cross-sectional study to analyze the mortality and disability-adjusted life years (DALYs) of SIDS across 204 countries and regions, stratified by sex, age, and sociodemographic index (SDI). Advanced methodologies included inequality analysis, frontier analysis to identify unfulfilled improvement potential, and risk factor quantification via meta-regression. Results: From 1990 to 2021, the global burden of SIDS demonstrated a substantial decline, with deaths decreasing from 75,719 to 30,608 and the mortality rate declining from 59.3 to 24.2 per 100,000 population. Males had higher mortality and DALYs rates compared to females, peaking at 51.9% in those aged 1 to 5 months. While absolute inequalities narrowed, relative disparities worsened. Frontier analysis revealed 15 high-priority countries (e.g., USA, Nigeria, India) with unfulfilled improvement potential despite socioeconomic advancement. Low birth weight and short gestation were identified as major risk factors, with the burden of SIDS attributable to these factors increasing after 2019. Conclusions: Despite an overall reduction in the global burden of SIDS, it remains a significant public health challenge with pronounced gender, age, and socioeconomic inequalities. However, significant heterogeneity in diagnostic practices and a well-documented shift in death certification from SIDS to broader classifications mean our results may underestimate the true decline in sudden unexpected infant deaths. To further reduce the burden of SIDS, targeted interventions are needed, focusing on perinatal health, addressing gender and age disparities, tackling region-specific air pollution issues, and prioritizing efforts in high-burden countries.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.