ArticleTranslational pediatrics2025
Risk factors of mortality among pediatric burn patients: a systematic review and meta-analysis.
Article in Translational pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Epidemiology, Management, and Alarmingly High Mortality of Burn Patients: A Retrospective Analysis From a Resource-Limited Tertiary Centre in Syria.International wound journal · 2026Article
- Pediatric scalp, face and neck burns in a referral pediatric burn centre in Türkiye.Frontiers in pediatrics · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Pediatric burn injuries remain a significant cause of morbidity and mortality worldwide. Identifying risk factors associated with mortality in this vulnerable population is critical for improving clinical outcomes and guiding preventive strategies. This systematic review and meta-analysis aimed to synthesize existing evidence on the risk factors of mortality among pediatric burn patients. Methods: A comprehensive search was conducted across PubMed, Embase, Web of Science, and Cochrane Library databases from inception to December 2024. Two reviewers independently screened studies, extracted data, and assessed quality. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using random-effects models. Sensitivity analysis and subgroup analysis were performed to assess the robustness of the findings and identify potential sources of heterogeneity. Results: Our meta-analysis incorporated 28 clinical studies comprising 5 cohort studies and 23 case-control studies, encompassing a total of 97,599 pediatric burn cases. The following ten parameters were identified as significant prognostic factors influencing mortality risk in pediatric burn patients-(I) total burn surface area (TBSA): extreme-value analysis (OR =1.17, 95% CI: 1.11-1.23; P<0.001), 10% (OR =12.65, 95% CI: 3.04-52.66; P<0.001), 25% (OR =58.44, 95% CI: 16.69-204.64; P<0.001); (II) age: extreme-value analysis (OR =0.93, 95% CI: 0.88-0.99; P=0.03), 4-year (OR =0.39, 95% CI: 0.19-0.80; P=0.01); (III) gender (female Conclusions: Our meta-analysis identified 10 risk factors associated with mortality in pediatric burn patients. Implementing multicenter prospective clinical studies may represent an effective strategy to address the current limitations of heterogeneity and bias in existing research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.