ArticleAIDS (London, England)2026
Lower working memory and processing speed among children and youth exposed to HIV.
Article in AIDS (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
objectivesTo compare cognitive function and identify correlates of lower cognitive functioning among children and youth exposed to HIV (CHEU) aged 7-18 years and peers unexposed to HIV (CHU).
designCross sectional survey.
methodsUsing the NIH Toolbox African Languages cognitive battery, we assessed working memory, attention and inhibitory control, episodic memory, cognitive flexibility, and processing speed. We compared domain scores between HIV exposure groups and determined correlates using multivariable linear regression adjusted for age and potential confounders.
resultsAmong 185 CHEU and 187 CHU assessed, median age was 12 years (interquartile range [IQR]: 10, 14) for CHEU and 13 (IQR: 10, 15) for CHU. CHEU were more likely to be orphaned and had older, less educated mothers. Among CHEU, 54.1% mothers started antiretroviral treatment prepregnancy. Compared to CHU, CHEU had significantly lower scores in working memory (adjusted β -1.2, 95% CI -2.0, -0.5, P = 0.002) and processing speed (adjusted β -4.9, 95% CI -7.3, -2.5, P < 0.001).Among CHEU, maternal combination ART in pregnancy was associated with better working memory; food insecurity was associated with poorer processing speed. In both groups, maternal education and child male sex were associated with better cognitive outcomes.
conclusionsCHEU experienced deficits in working memory and processing speed compared to CHU. Discerning mechanisms for CHEU could inform interventions. Ensuring maternal ART and addressing food insecurity among CHEU may enhance cognitive outcomes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.