Evidence map›Paper›PMID 41217621›Full record

ReviewJournal of cancer survivorship : research and practice2025

Sedentary behavior in children, adolescents, and young adults treated for cancer: A scoping review of health outcomes and interventions.

Brittany J Ivory, Kristen Moore, Jennifer E Dinalo, Nina S Kadan-Lottick, Christina M Dieli-Conwright, Etan Orgel, Kirsten K Ness, David R Freyer, Britni R Belcher

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of cancer survivorship : research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Brittany J IvoryCancer and Blood Disease Institute, Children's Hospital Los Angeles, 4650 Sunset Blvd, MS #54, Los Angeles, CA, 90027, USA. bivory@chla.usc.edu.
Kristen MooreDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Jennifer E DinaloSouthern California Evidence Review Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Nina S Kadan-LottickDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.
Christina M Dieli-ConwrightDivision of Population Sciences, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
Etan OrgelCancer and Blood Disease Institute, Children's Hospital Los Angeles, 4650 Sunset Blvd, MS #54, Los Angeles, CA, 90027, USA.
Kirsten K NessDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, USA.
David R FreyerCancer and Blood Disease Institute, Children's Hospital Los Angeles, 4650 Sunset Blvd, MS #54, Los Angeles, CA, 90027, USA.
Britni R BelcherDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAlthough sedentary behavior (SB) is linked to adverse health outcomes in adult cancer populations, its health impact and the effectiveness of SB interventions in younger patients remain underexplored. This scoping review examined (1) associations between SB and health outcomes and (2) intervention studies to reduce SB among childhood and AYA cancer patients and survivors.

methodsA search of five databases (PubMed, Embase, Web of Science, CINAHL, SportDiscus) was finalized in May 2025. Studies were included if ≥ 50% of participants were ≤ 39 years old and treated for cancer, and SB was measured via device or self-report. Observational studies had to report associations of SB with health outcomes; intervention studies had to report results for SB-related aims. Risk of bias and quality assessments were performed using established tools.

resultsTwenty-four studies (16 observational, 8 interventional) met criteria. Observational studies identified associations between SB and adverse cardiometabolic, bone, and patient-reported outcomes; none assessed mortality. All interventions primarily targeted physical activity, not SB reduction; three showed modest, short-term SB decreases.

conclusionsEarly evidence suggests SB is associated with multiple adverse health outcomes in youth treated for cancer, while current interventions without an SB-specific focus have minimal impact. Key research gaps include the absence of longitudinal data, standardized SB measurement, and randomized controlled trials testing SB-focused strategies. IMPLICATIONS FOR CANCER SURVIVORS: Reducing SB may help mitigate health risks in childhood and AYA cancer survivors. More robust epidemiologic evidence and targeted interventions are needed to address this modifiable behavior.

Indexed as

Adolescent and young adult (AYA) cancerBehavioral interventionsCancer survivorsChildhood cancerHealth outcomesSedentary behavior

Identifiers

PMID41217621

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.