ArticleJournal of Korean medical science2025
Investigation of the Impact of Body Mass Index in the 20s on Chronic Metabolic Diseases and Their Progression Rate After the Age of 65 Years.
Article in Journal of Korean medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundIn this study, we aimed to evaluate the relationship between the body mass index (BMI) of participants in their 20s (20s_BMI) and the risk of developing various chronic metabolic diseases when they were over the age of 65 years. We also investigated how quickly these values worsened after 65 years of age.
methodsThis 8-year prospective cohort study targeted elderly people aged 65 years or older with three healthcare visits at 3-4 to year intervals. Participants were divided into four groups according to their 20s_BMI and the occurrence and changes in body weight and fatty liver were observed for approximately 8 years.
resultsA total of 1,130 people aged 65 years or older were included. In the 65-69 years age group, as the 20s_BMI increased, weight, BMI, waist circumference, and hip circumference all significantly increased (all
conclusionWe found that a high 20s_BMI continued to be high even after the age of 65 years and had a negative impact on the occurrence and worsening of metabolic dysfunction-associated steatotic liver disease. This suggests that weight management starting in the 20s is important to prevent the progression of chronic diseases after the age of 65 years.
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