Evidence map›Paper›PMID 41219510›Full record

Observational studyJournal of perinatology : official journal of the California Perinatal Association2026

Oxidative stress and fetal weight: observational findings from a pregnancy cohort in New York City.

Carol Duh-Leong, Akhgar Ghassabian, Whitney Cowell, Sarvenaz Shahin, Mengling Liu, Kurunthachalam Kannan, Kristyn A Pierce, Shilpi S Mehta-Lee, Sara E Long, Yuyan Wang and 3 more

Abstract readObservational Study
In one paragraph

Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Carol Duh-LeongDepartment of Pediatrics, NYU Grossman School of Medicine, New York, NY, USA. carol.duh-leong@nyulangone.org.ORCID http://orcid.org/0000-0001-5648-580X
Akhgar GhassabianDepartment of Pediatrics, NYU Grossman School of Medicine, New York, NY, USA.
Whitney CowellDepartment of Pediatrics, NYU Grossman School of Medicine, New York, NY, USA.
Sarvenaz ShahinDepartment of Pediatrics, NYU Grossman School of Medicine, New York, NY, USA.
Mengling LiuDepartment of Population Health, NYU Grossman School of Medicine, New York, NY, USA.
Kurunthachalam KannanDepartment of Pediatrics, NYU Grossman School of Medicine, New York, NY, USA.
Kristyn A PierceDepartment of Pediatrics, NYU Grossman School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0003-0892-5393
Shilpi S Mehta-LeeDepartment of Obstetrics and Gynecology, NYU Grossman School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0001-8126-9631
Sara E LongDepartment of Pediatrics, NYU Grossman School of Medicine, New York, NY, USA.
Yuyan WangDepartment of Population Health, NYU Grossman School of Medicine, New York, NY, USA.
Wenqing YangDepartment of Population Health, NYU Grossman School of Medicine, New York, NY, USA.
Yelena AfanasyevaDepartment of Population Health, NYU Grossman School of Medicine, New York, NY, USA.
Leonardo TrasandeDepartment of Pediatrics, NYU Grossman School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-1928-597X

Funding

Geospatial food access as a driver of environmental oxidant stressors and early obesityK23ES035461 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Carol Duh-Leong · 2023 to 2026
$1.0M
Particulate air pollution, pregnancy outcomes, and the role of placental extracellular microRNAsR00ES032029 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COWELL, WHITNEY · 2022 to 2024
$745k
NIEHS NIH HHS K23 ES035461NIEHS NIH HHS R00 ES032029U.S. Department of Health & Human Services | NIH | National Institute of Environmental Health Sciences (NIEHS) K23ES035461U.S. Department of Health & Human Services | NIH | National Institute of Environmental Health Sciences (NIEHS) R00ES032029U.S. Department of Health & Human Services | NIH | NIH Office of the Director (OD) UG3/UH3OD023305
6 · The paper itself

Abstract

objectiveTo examine associations between oxidative stress and fetal weight across pregnancy. STUDY

designCohort study of pregnant participants from 2016-2021 in New York City with urinary lipid, protein, and DNA oxidative stress biomarkers (<18, 18-25, >25 weeks) and estimated fetal weight from ultrasound fetal biometry with the HadlockIII formula (20, 30, 36 weeks).

resultAmong 1408 participants, oxidative stress biomarkers of lipid peroxidation and DNA damage were associated with smaller estimated fetal weight at 30 and 36 weeks (ranging from B = -3.9 grams/unit increase [95% CI: -6.9, -0.9; 8,15 - PGF2α] to -20.3 [95% CI: -27.9, -12.8; 8 - OHdG]), particularly among fetuses at the 25

conclusionThese findings advance our understanding of different oxidative stress pathways and their potential role in fetal growth.

Indexed as

Fetal WeightOxidative StressAdultBiomarkersCohort StudiesFemaleGestational AgeHumansLipid PeroxidationNew York CityPregnancyUltrasonography, PrenatalYoung AdultBiomarkers

Identifiers

PMID41219510
PMCPMC12662709

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.