ReviewThe Canadian journal of urology2025
Evaluation and research progress on rodent models of late-onset hypogonadism: a comprehensive review.
Review in The Canadian journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
Funding
Abstract
Late-onset hypogonadism (LOH), characterized by the intersection of aging and androgen deficiency, impacts the health of approximately 2%-39% of middle-aged and elderly men, underscoring the need for comprehensive research. Animal models, serving as analogs of human diseases, are indispensable for investigating disease mechanisms and facilitating drug development. However, the diverse array of animal models utilized for LOH research has led to a lack of standardized modeling approaches and evaluation systems, potentially impeding progress in understanding the pathogenesis and therapeutic development. In this paper, we summarize and compile the characteristics, methods, and evaluation systems of rodent models for LOH research reported in the literature, and analyze the advantages and disadvantages of each model, to facilitate the optimal choice and development of rodent models for LOH research.
Indexed as
Identifiers
41220349What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.