Evidence map›Paper›PMID 41220825›Full record

ArticleERJ open research2025

Maternal asthma and lung function, childhood asthma and growth: the MAESTRO-Child study.

Emma Caffrey Osvald, Cecilia Lundholm, Bronwyn K Brew, Hanna Karim, Gustaf Rejnö, Samuel Rhedin, Catarina Almqvist

Abstract read
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emma Caffrey OsvaldDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-3367-694X
Cecilia LundholmDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Bronwyn K BrewDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Hanna KarimDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Gustaf RejnöDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-8095-5629
Samuel RhedinDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Catarina AlmqvistDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Maternal asthma is associated with childhood asthma and low birthweight. We investigated whether maternal asthma, allergic asthma and lung function are associated with childhood asthma and growth. Method: Data from a Swedish pregnancy cohort (Maternal Asthma Events Stress and Offspring (MAESTRO)) were linked to data from children (MAESTRO-Child) and to national health registers (529 mother-child pairs). Pre- and post-bronchodilator forced expiratory volume in 1 s (FEV Results: For maternal allergic asthma, there was an increased risk of "asthma ever by 6 years" (adjusted risk ratio (adjRR) 2.07, 95% confidence interval (CI) 1.33-3.22). Increasing pre- and post-bronchodilator FEV Conclusion: Maternal asthma and allergic asthma are risk factors for childhood asthma. Higher lung function in pregnancy may be associated with a lower risk for childhood asthma in the offspring. Maternal measures did not have a statistically significant association with childhood growth in the offspring.

Identifiers

PMID41220825
PMCPMC12598613

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.