ArticleDalton transactions (Cambridge, England : 2003)2025
Engineered mesoporous silica nanosystems with organotin(IV) complexes containing 1-(quinolin-8-yliminomethyl)naphthalen-2-ol ligand for cancer cell targeting.
Article in Dalton transactions (Cambridge, England : 2003), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Pro-Apoptotic Organometallic Sn(IV) Bis-Organosilane Benzoate Complexes with Sustained Reduction in Cell Viability Under Resistance-like Conditions in Colorectal Cancer Cells.International journal of molecular sciences · 2026Article
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7 authors.
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Abstract
The development of targeted nanotherapeutics has emerged as a promising approach to improve the efficacy and safety of anticancer treatments. This manuscript presents the synthesis, detailed characterization, and biological evaluation of novel mesoporous silica nanoparticles (sMSNs) functionalized with organotin(IV) complexes containing 1-(quinolin-8-yliminomethyl)naphthalen-2-ol ligand, which have also been selectively targeted using biotin (BT) and folic acid (FA). The systems have been comprehensively characterized using microscopy, nitrogen adsorption-desorption isotherms, and several spectroscopic methods confirming the successful conjugation of organotin(IV) complexes and targeting ligands, as well as the preservation of the structural integrity of the nanoparticles. The cytotoxic potential of the functionalized sMSNs was assessed
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