Evidence map›Paper›PMID 41223030›Full record

ArticleAIDS care2026

Pre-Exposure prophylaxis knowledge, use and adherence among a US national sample of women.

Samira Gure, Jean Jimenez, Maeve Brin, Mirjam-Collette Kempf, Amy K Johnson, Jianfang Liu, Monica Gandhi, Gina Wingood, Gregory Phillips Ii, Jodie A Dionne and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Samira GureSchool of Nursing, Columbia University, New York, NY, USA.
Jean JimenezSchool of Nursing, Columbia University, New York, NY, USA.
Maeve BrinSchool of Nursing, Columbia University, New York, NY, USA.
Mirjam-Collette KempfSchool of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
Amy K JohnsonAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
Jianfang LiuSchool of Nursing, Columbia University, New York, NY, USA.
Monica GandhiSan Francisco School of Medicine, University of California, San Francisco, CA, USA.
Gina WingoodSchool of Nursing, Columbia University, New York, NY, USA.
Gregory Phillips IiDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Jodie A DionneHeersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Robert KlitzmanDepartment of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Tonda L HughesSchool of Nursing, Columbia University, New York, NY, USA.
Jessica Lee CorcoranDepartment of Family, Community, and Health Systems, School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Dustin Marsh LongDepartment of Biostatistics and Data Science, School of Medicine, Wake Forest University, Winston-Salem, NC, USA.
Ariann F NasselSchool of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
Rebecca SchnallSchool of Nursing, Columbia University, New York, NY, USA.

Funding

Examining Social Ecological and Network Factors to Assess Epidemiological Risk in a Large National Cohort of Cisgender WomenR01AI172469 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Amy Kristen Johnson, MIRJAM-COLETTE KEMPF · 2022 to 2026
$12.1M
NIAID NIH HHS R01 AI172469
6 · The paper itself

Abstract

Pre-exposure prophylaxis (PrEP) is a proven strategy for HIV prevention, yet uptake among women vulnerable to HIV remains low. This study draws on survey data and urine-based adherence testing from the American Women Assessing Risk Epidemiologically (AWARE) study to assess PrEP knowledge, use, and adherence in a behaviorally vulnerable sample. Despite high awareness of PrEP, actual use and willingness to consider PrEP were minimal. Objective adherence testing showed that most women who self-reported current PrEP use adhered to the daily regimen. Findings suggest that socioeconomic status, insurance coverage, relationship dynamics, and health literacy influence PrEP engagement. The small number of PrEP users underscores persistent barriers, including misinformation and medication affordability. Addressing these factors is critical to converting awareness into sustained use. Future prevention efforts should prioritize improving PrEP health literacy and expanding access to affordable medication. These findings highlight the need for targeted interventions that address the intersecting structural and informational barriers to PrEP uptake among women in the U.S.

Indexed as

Anti-HIV AgentsHealth Knowledge, Attitudes, PracticeHIV InfectionsMedication AdherencePre-Exposure ProphylaxisAdolescentAdultFemaleHealth LiteracyHumansMiddle AgedSocioeconomic FactorsSurveys and QuestionnairesUnited StatesYoung AdultAnti-HIV AgentsadherenceGender equalityGood health and well-beingHIVPre-exposure prophylaxisReduced inequalitiestenofovirwomen

Identifiers

PMID41223030
PMCPMC13005950

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.