Evidence map›Paper›PMID 41224662›Full record

ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2025

No Central Executive? Decision Formation Through Multi-Area Population Dynamics.

Chandramouli Chandrasekaran, Diksha Gupta, Mitra Javadzadeh, Tian Wang, Miguel Vivar-Lazo, Tatiana Engel, Paul Cisek, Christopher R Fetsch

Abstract readReview
In one paragraph

Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chandramouli ChandrasekaranAnatomy & Neurobiology, and Psychological and Brain Sciences, Boston University, Boston, Massachusetts cchandr1@bu.edu.ORCID 0000-0002-1711-590X
Diksha GuptaSainsbury Wellcome Centre, University College London, London WC1E 6BT, United Kingdom.
Mitra JavadzadehCold Spring Harbor Laboratory, Cold Spring Harbor, New York.
Tian WangDepartment of Biomedical Engineering, Boston University, Boston, Massachusetts.
Miguel Vivar-LazoDepartment of Neuroscience & Zuckerman Institute, Columbia University, New York, New York.ORCID 0009-0008-2798-1239
Tatiana EngelPrinceton Neuroscience Institute, Princeton, New Jersey.ORCID 0000-0001-5842-9406
Paul CisekDepartment of Neuroscience, University of Montreal, Montreal, Quebec H3T 1J4, Canada.ORCID 0000-0001-7060-7287
Christopher R FetschDepartment of Neuroscience & Zanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, Maryland.ORCID 0000-0002-7921-8306

Funding

Cortical circuit dynamics underlying multisensory decision makingRF1NS132910 · NINDS · JOHNS HOPKINS UNIVERSITY · PI FETSCH, CHRISTOPHER R · 2023 to 2023
$1.5M
NINDS NIH HHS RF1 NS132910
6 · The paper itself

Abstract

Perceptual decision-making is the process by which sensory evidence is combined with prior knowledge and transformed into possible movement plans according to a rule or policy. Classic studies suggested that perceptual decisions emerge from a feedforward hierarchy of brain areas with distinct functions and fairly homogeneous neural representations. However, more recent findings argue that decisions emerge from distributed, recurrent computations across many brain areas (a "heterarchy") with complex, heterogeneous representations. How can we make sense of these findings in a way that preserves the computational elegance of the conventional view? In this review, we describe how a new generation of studies is leveraging high-density electrophysiology, incisive task designs, causal manipulations (e.g., optogenetics) and statistical approaches for probing inter-area communication, and theoretical methods that connect population dynamics with representational geometry to build a modern framework for understanding perceptual decisions.

Indexed as

BrainDecision MakingExecutive FunctionAnimalsHumansModels, NeurologicalPopulation Dynamics

Identifiers

PMID41224662
PMCPMC12614049

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.