ArticleThe Journal of international medical research2025
Fibrinogen and cytokines as biomarkers of ovarian hyperstimulation syndrome in women undergoing assisted reproductive technology treatment: A prospective cohort study.
Article in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
BackgroundOvarian hyperstimulation syndrome is the most severe and life-threatening iatrogenic complication of controlled ovarian stimulation during assisted reproductive technology procedures. Its diagnosis and severity grading are complex. Despite its debilitating and sometimes fatal consequences, there is a paucity of data on early predictors of ovarian hyperstimulation syndrome.ObjectiveThis study aimed to identify early predictors of ovarian hyperstimulation syndrome among women undergoing controlled ovarian stimulation for assisted reproductive technology treatment.MethodsThis prospective cohort study included 46 women undergoing assisted reproductive technology treatment from 1 April to 30 November 2023 at Hallmark Medicals, Kumasi, Ghana. Participants were conveniently recruited and received a standard controlled ovarian stimulation protocol. A structured questionnaire was used to collect sociodemographic and clinical data. Approximately 10 mL of venous blood was collected for laboratory analysis of fibrinogen and cytokine markers as well as hepatic and renal function tests. Statistical analyses were performed using R version 4.3.2 and Statistical Package for the Social Sciences version 26.0. A
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