Evidence mapPaperPMID 41224701Full record

ArticleThe Journal of international medical research2025

Fibrinogen and cytokines as biomarkers of ovarian hyperstimulation syndrome in women undergoing assisted reproductive technology treatment: A prospective cohort study.

Herbert Ekoe Dankluvi, Enoch Odame Anto, Benedict Sackey, Ebenezer Senu, Elikplim Adzo Damalie, Millicent Osaah, Ellis Fleischer Djoleto, Edward Dassah, Charles Mawunyo Senaya, Francis Jojo Moses Kwadzo Damalie

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Article in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Herbert Ekoe DankluviDepartment of Medical Diagnostics, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Ghana.
Enoch Odame AntoDepartment of Medical Diagnostics, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Ghana.ORCID 0000-0001-9023-6612
Benedict SackeyDepartment of Medical Diagnostics, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Ghana.
Ebenezer SenuDepartment of Molecular Medicine, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Ghana.
Elikplim Adzo DamalieHallmark Medicals, Ghana.
Millicent OsaahHallmark Medicals, Ghana.
Ellis Fleischer DjoletoHallmark Medicals, Ghana.
Edward DassahDepartment of Population, Family and Reproductive Health, School of Public Health, Kwame Nkrumah University of Science and Technology, Ghana.
Charles Mawunyo SenayaDirectorate of Obstetrics and Gynaecology, Komfo Anokye Teaching Hospital, Ghana.
Francis Jojo Moses Kwadzo DamalieHallmark Medicals, Ghana.ORCID 0009-0009-8069-8114

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundOvarian hyperstimulation syndrome is the most severe and life-threatening iatrogenic complication of controlled ovarian stimulation during assisted reproductive technology procedures. Its diagnosis and severity grading are complex. Despite its debilitating and sometimes fatal consequences, there is a paucity of data on early predictors of ovarian hyperstimulation syndrome.ObjectiveThis study aimed to identify early predictors of ovarian hyperstimulation syndrome among women undergoing controlled ovarian stimulation for assisted reproductive technology treatment.MethodsThis prospective cohort study included 46 women undergoing assisted reproductive technology treatment from 1 April to 30 November 2023 at Hallmark Medicals, Kumasi, Ghana. Participants were conveniently recruited and received a standard controlled ovarian stimulation protocol. A structured questionnaire was used to collect sociodemographic and clinical data. Approximately 10 mL of venous blood was collected for laboratory analysis of fibrinogen and cytokine markers as well as hepatic and renal function tests. Statistical analyses were performed using R version 4.3.2 and Statistical Package for the Social Sciences version 26.0. A

Indexed as

BiomarkersCytokinesFibrinogenOvarian Hyperstimulation SyndromeOvulation InductionReproductive Techniques, AssistedAdolescentAdultFemaleGhanaHumansIncidenceProspective StudiesROC CurveYoung AdultBiomarkersCytokinesFibrinogenbiomarkerscontrolled ovarian stimulationOvarian hyperstimulation syndromepreventionrisk factors

Identifiers

PMID41224701
PMCPMC12615939

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.