ArticleScientific reports2025
Antibacterial properties of bioengineered silver nanoparticles from Pastinaca sativa against Enterococcus faecalis biofilms in endodontic therapy.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Green synthesis of silver nanoparticles under ambient conditions using onion, turmeric, and galangal extracts with antibacterial activity againstBiotechnology reports (Amsterdam, Netherlands) · 2026Article
- Silver Nanoparticles fromACS omega · 2026Article
- In Vivo Wound Healing Activity Using Pomegranate Peel Derived - Silver Nanoparticle Hydrogel Pre-Exposed with 660 nm Red Light.Biological trace element research · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectiveEndodontic therapy often faces the challenge of complete infection eradication and preventing recurrence, with Enterococcus faecalis (E. faecalis) being the most significant cause of treatment failure. Using materials with antibacterial and anti-biofilm properties can increase the success rate of endodontic treatment. Therefore, this study investigated the properties of silver nanoparticles synthesized using Pastinaca sativa (P. sativa) root extract (Ag@PSR).
methodsIn this study, P. sativa root extract was used as both the reducing and stabilizing agent. Synthesis parameters (silver nitrate concentration, time, and temperature) were optimized using UV-Vis spectroscopy. Characterization analyses, including XRD, FTIR, FESEM, and TEM, were performed on the Ag@PSR nanoparticles. The antibacterial, anti-biofilm, and antioxidant properties of Ag@PSR nanoparticles were also investigated.
resultsOptimal reaction conditions were determined to be a 15 mM silver nitrate concentration, a temperature of 85 °C, and a reaction time of 15 min for the synthesis of Ag@PSR nanoparticles. XRD analysis confirmed the synthesis of silver nanoparticles. FTIR analysis confirmed the presence of functional groups from the extract within the Ag@PSR structure. Morphological and size analysis using FESEM and TEM images revealed the formation of spherical, uniform nanoparticles with sizes ranging from 15 to 40 nm. Antibacterial assays revealed that Ag@PSR exhibited an MIC of 500 µg/mL against E. faecalis. Similar inhibitory activity was also observed against other tested strains. Moreover, Ag@PSR reduced E. faecalis biofilm formation by 86.7%. These nanoparticles also scavenged 91% of DPPH radicals at a concentration of 500 µg/mL.
conclusionThese results indicate the high potential of Ag@PSR nanoparticles as a multifaceted agent for treating oral infections and improving dental materials, especially in endodontics.
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