ArticleCommunications biology2025
Differential dopaminergic modulation of the antennal lobe of Drosophila melanogaster.
Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Bioamine disruption leads to memory deficits in the whip spider, Phrynus marginemaculatus.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Article
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Authors and funding
2 authors.
Funding
Abstract
Olfaction plays a key role in the ability of organisms to monitor their ever-changing chemical environment. Dopamine is a key modulator of the mammalian and insect nervous systems, including the fruit fly Drosophila melanogaster. While there are few indications for dopamine signaling in the fly's first-order olfactory processing center, the antennal lobe (AL), the role of dopamine in Drosophila early olfactory processing remains unknown. Here we reveal broad dopamine receptor expression in key AL cell types. Dopamine application differentially modulates AL output in an odor-dependent manner. Furthermore, we identify AL-innervating neurons expressing the marker for dopaminergic cells, tyrosine hydroxylase, and show that activation of these neurons leads to dopamine release in the AL. Finally, we find that endogenous dopamine release affects AL output in a similar manner to dopamine application.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.