ReviewAdvances in experimental medicine and biology2026
Titanium Dental Implant Corrosion in Peri-Implantitis and Implant Failure.
Review in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Titanium Degradation Products from Dental Implants: Mechanisms of Release, Biodistribution, and Analytical Detection in Biological Matrices.International journal of molecular sciences · 2026Review
- A Redox Amplification Interface Linking Mitochondrial Dysfunction, Immune-Derived Oxidants, and Biomaterial Electrochemistry in Chronic Inflammation.International journal of molecular sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Titanium (Ti) is an inert metallic element with the atomic number 22. It is alloyed with other elements to create strong, lightweight materials like titanium alloy Ti6Al4V, a titanium alloy composed of 90% titanium, 6% aluminum, and 4% vanadium. These alloys have been widely used in dentistry and surgery for their biocompatibility, mechanical strength, and corrosion resistance. A key feature of titanium implants is their ability to osseointegrate with bone, creating a stable connection between the implant and the surrounding bone tissue. Titanium naturally forms a protective oxide layer during implant placement, enhancing its corrosion resistance. However, continuous exposure to the oral environment poses challenges that may lead to its degradation and corrosion. This process releases metal ions, microparticles, and nanoparticles into the surrounding tissues, triggering local and systemic inflammatory reactions. Alongside bacterial infection and mechanical wear, this corrosion can exacerbate peri-implant inflammatory diseases, such as mucositis and peri-implantitis, potentially leading to implant failure.This chapter explores the mechanisms of titanium implant corrosion, risk factors accelerating the process, the role of titanium hypersensitivity in response to corrosion by-products, as well as its effects on implant success. Furthermore, it explores how corrosion contributes to peri-implant inflammation and affects the surrounding peri-implant tissues. It also highlights strategies to minimize corrosion, including the use of innovative materials in implant coatings and surface treatments, and concludes by discussing potential future research directions.
Indexed as
Identifiers
41225111What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.