Evidence mapPaperPMID 41226113Full record

ArticleMolecules (Basel, Switzerland)2025

Potential Antiviral Compounds from

Eliza Flores-Souza, Alisson Samuel Portes Caldeira, Carolina Colombelli Pacca-Mazaro, Tamiris Vanessa Miguel de Souza, Thaís Magalhães Acácio, Emerson de Castro Barbosa, Naiara Clemente Tavares, Carlos Eduardo Calzavara-Silva, Carlos Leomar Zani, Douglas Eduardo Valente Pires and 2 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Eliza Flores-SouzaGrupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.ORCID 0000-0002-6548-147X
Alisson Samuel Portes CaldeiraGrupo de Pesquisa de Química de Produtos Naturais Bioativos, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.ORCID 0000-0002-0998-1939
Carolina Colombelli Pacca-MazaroGrupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.
Tamiris Vanessa Miguel de SouzaGrupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.ORCID 0009-0000-7822-8791
Thaís Magalhães AcácioGrupo de Pesquisa de Química de Produtos Naturais Bioativos, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.ORCID 0000-0002-1871-9860
Emerson de Castro BarbosaGrupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.ORCID 0000-0002-3210-7342
Naiara Clemente TavaresGrupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.
Carlos Eduardo Calzavara-SilvaGrupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.ORCID 0000-0002-1406-6401
Carlos Leomar ZaniGrupo de Pesquisa de Química de Produtos Naturais Bioativos, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.ORCID 0000-0003-1859-177X
Douglas Eduardo Valente PiresSchool of Computing and Information Systems, The University of Melbourne, Melbourne 3010, Australia.ORCID 0000-0002-3004-2119
Tânia Maria de Almeida AlvesGrupo de Pesquisa de Química de Produtos Naturais Bioativos, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.ORCID 0000-0002-0582-3968
Jaquelline Germano de OliveiraGrupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.ORCID 0000-0002-0487-8748

Funding

Fundação de Amparo à Pesquisa do Estado de Minas Gerais 5941634243
6 · The paper itself

Abstract

Despite the availability of effective vaccines, yellow fever outbreaks persist, highlighting the need for antiviral drugs. BACKGROUND/

objectivesThis study investigated METHODS/

resultsThe crude bulb extract of

conclusionsOur results underscore the importance of further investigations

Indexed as

AmaryllidaceaeAntiviral AgentsPlant ExtractsPlant RootsYellow fever virusAnimalsBiological AssayChlorocebus aethiopsComputer SimulationHumansVero CellsYellow FeverAntiviral AgentsPlant Extractsantiviralsbioassay-guided fractionationHippeastrum puniceumIn silico ADMET predictionsecondary metaboliteswild-type yellow fever virus

Identifiers

PMID41226113
PMCPMC12608337

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.