Evidence map›Paper›PMID 41226138›Full record

ArticleMolecules (Basel, Switzerland)2025

Hyperpolarized Carbon-13 Metabolic Imaging Differentiates Distinctive Molecular Phenotypes in Diffuse Midline Gliomas.

Ilwoo Park, Rintaro Hashizume, Joanna Phillips

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ilwoo ParkDepartment of Radiology, Chonnam National University Medical School and Hospital, Gwangju 61469, Republic of Korea.
Rintaro HashizumeDepartment of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA.ORCID 0000-0002-9373-7831
Joanna PhillipsDepartment of Neurological Surgery and Pathology, University of California, San Francisco, CA 94143, USA.

Funding

Tissue CoreP50CA097257 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MITCHEL S. BERGER · 2002 to 2026
$57.4M
Targeting Transcriptional Elongation in Pediatric GliomaR01NS126513 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Rintaro Hashizume · 2022 to 2026
$1.9M
Regulating the glioma immune microenvironmentR01NS131474 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Joanna Phillips · 2024 to 2026
$1.8M
Chonnam National University 2023-0083Chonnam National University Hospital Biomedical Research Institute BCRI25010Institute of Information & communications Technology Planning & Evaluation IITP-2023-RS-2023-00256629NCI NIH HHS P50 CA097257NIH HHS 1R01NS126513-25NINDS NIH HHS R01 NS126513NINDS NIH HHS R01 NS131474
6 · The paper itself

Abstract

Despite a specific histone mutation defining the unique genetic makeup, diffuse midline gliomas are heterogeneous tumors with a wide range of morphologic and molecular spectrum. We investigated the feasibility of using hyperpolarized carbon-13(

Indexed as

Brain NeoplasmsCarbon IsotopesGliomaMolecular ImagingAnimalsCell Line, TumorHistonesHumansLactic AcidL-Lactate DehydrogenaseMagnetic Resonance ImagingPhenotypePyruvic AcidRatsCarbon-13Carbon IsotopesHistonesLactic AcidL-Lactate DehydrogenasePyruvic Aciddiffuse midline gliomahyperpolarized carbon-13magnetic resonance imagingmetabolic imagingpediatric brain tumor

Identifiers

PMID41226138
PMCPMC12608448

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.