Evidence map›Paper›PMID 41226150›Full record

ReviewMolecules (Basel, Switzerland)2025

Modern Developing Directions in the Dihydroquercetin Study.

Svetlana Yu Filippovich, Elena P Isakova, Galina P Bachurina, Yulia I Deryabina

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Svetlana Yu FilippovichA.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Leninsky Ave. 33/2, 119071 Moscow, Russia.ORCID 0000-0001-9615-5805
Elena P IsakovaA.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Leninsky Ave. 33/2, 119071 Moscow, Russia.
Galina P BachurinaA.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Leninsky Ave. 33/2, 119071 Moscow, Russia.
Yulia I DeryabinaA.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Leninsky Ave. 33/2, 119071 Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dihydroquercetin (taxifolin) is a natural bioflavonoid with diverse biological activities, including antioxidant, anti-inflammatory, antibacterial, antiviral, and geroprotective effects. The review summarizes current advances in the research of dihydroquercetin with a focus on its structural features, physicochemical properties, and biological functions. Particular attention is drawn to its low solubility and limited bioavailability, which have stimulated the development of nanotechnology-based delivery systems. In the paper, the systematization of the systems, namely nanoparticles, liposomes, hydrogels, nanofibers, nanoenzymes, and crystalline complexes, is presented. Moreover, some specific features of the antibacterial and antiviral action of the compound are described. Recent findings on the molecular mechanisms of action, including regulation of oxidative stress and cellular signaling pathways, highlight the therapeutic promise of dihydroquercetin. Taken together, the data support its potential as a valuable compound for pharmaceutical and biomedical applications, though further comprehensive investigations are required.

Indexed as

QuercetinAnimalsAnti-Bacterial AgentsAntioxidantsAntiviral AgentsDrug Delivery SystemsHumansNanoparticlesAnti-Bacterial AgentsAntioxidantsAntiviral AgentsQuercetintaxifolinantiageantibacterialantiviralbioavailabilitydihydroquercetinnanotechnologysolubility

Identifiers

PMID41226150
PMCPMC12609695

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.