ReviewMolecules (Basel, Switzerland)2025
Vitamin-Conjugated Metallic Nanoparticles: Applications for Antimicrobial and Anti-Cancer Drug Delivery.
Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Zwitterionic Surfactant-Based Silica Nanofluid for Enhanced Oil Recovery: Oil Displacement Behavior and Mechanisms.Molecules (Basel, Switzerland) · 2026Article
- Perspective Approaches to "Trojan Horse" Strategy Development for Combating Bacterial Pathogens.Pharmaceuticals (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Vitamin-conjugated metallic nanoparticles (VC-MNPs) have emerged as a transformative platform in nanomedicine that combine the therapeutic potential of vitamins with the structural versatility of metal nanoparticles. They offer a dual advantage of targeted drug delivery and enhanced therapeutic efficacy, enabling precise intervention against infectious and malignant diseases. Vitamin conjugation facilitates receptor-mediated targeting, antioxidant enhancement, and improved biocompatibility, thereby strengthening therapeutic outcomes and reducing off-target effects. This review critically evaluates how vitamin functionalization modulates the synthesis, activity, and clinical translation of VC-MNPs. Diverse synthesis methods including chemical reduction, co-precipitation, sol-gel, and green approaches are evaluated, along with the influence of synthesis parameters on nanoparticle performance. The mechanisms underlying enhanced antimicrobial and anti-cancer efficacy are discussed, highlighting the contributions of vitamin functionalization to cellular uptake, redox balance and metabolic selectivity. Critical challenges in clinical translation are systematically assessed, including nanoparticle stability under physiological conditions, potential toxicity concerns, regulatory approval pathways, and manufacturing scalability requirements. Finally, the paper considers future perspectives, focusing on synthesis innovations, novel therapeutic targets, interdisciplinary collaborations, and pathways for clinical translation. Overall, VC-MNPs represent a promising next-generation platform for precision nanomedicine and sustainable therapeutic design.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.