Evidence map›Paper›PMID 41226258›Full record

ArticleMolecules (Basel, Switzerland)2025

Screening of Cytotoxic and Genotoxic Activities of Subcritical Water Extracts from

Tsvetelina Gerasimova, Svetla Gateva, Gabriele Jovtchev, Ana Dobreva, Milka Mileva, Zlatina Kokanova-Nedialkova, Milena Gospodinova, Tsveta Angelova, Paraskev Nedialkov

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Biogenesis of Au Nanoparticles from Plant-Derived Metabolites -ACS biomaterials science & engineering · 2026
    Article
  4. Biostimulants fromFrontiers in plant science · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tsvetelina GerasimovaInstitute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 2 Gagarin Str., 1113 Sofia, Bulgaria.ORCID 0000-0002-5661-9721
Svetla GatevaInstitute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 2 Gagarin Str., 1113 Sofia, Bulgaria.ORCID 0000-0002-6567-831X
Gabriele JovtchevInstitute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 2 Gagarin Str., 1113 Sofia, Bulgaria.ORCID 0000-0002-0170-4718
Ana DobrevaInstitute for Roses and Aromatic Plants, Agricultural Academy, 49 Osvobojdenie Blvd., 6100 Kazanlak, Bulgaria.ORCID 0000-0002-4241-9817
Milka MilevaThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Str., 1113 Sofia, Bulgaria.ORCID 0000-0002-3218-4487
Zlatina Kokanova-NedialkovaDepartment of Pharmacognosy, Faculty of Pharmacy, Medical University of Sofia, 2 Dunav Str., 1000 Sofia, Bulgaria.ORCID 0000-0002-1553-6428
Milena GospodinovaInstitute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 2 Gagarin Str., 1113 Sofia, Bulgaria.ORCID 0000-0003-1621-5949
Tsveta AngelovaInstitute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 2 Gagarin Str., 1113 Sofia, Bulgaria.ORCID 0000-0001-9939-1889
Paraskev NedialkovDepartment of Pharmacognosy, Faculty of Pharmacy, Medical University of Sofia, 2 Dunav Str., 1000 Sofia, Bulgaria.ORCID 0000-0001-5640-6120

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regulatory changes in the EU for safety purposes require strict control and high safety standards for essential oils obtained by steam distillation, as they are classified as chemical mixtures with potential toxic effects. Subcritical water extracts (SWEs) are considered safer. This study evaluated the cytotoxicity and genotoxicity of SWEs from

Indexed as

FlowersPlant ExtractsRosaAnimalsChromosome AberrationsDNA DamageHordeumHumansLymphocytesMiceMicronucleus TestsMutagenicity TestsWaterPlant ExtractsWaterbioactive compoundscytogenetic testscytotoxicitygenotoxicityin vitro test systemin vivo test systemsrose subcritical water extracts

Identifiers

PMID41226258
PMCPMC12610300

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.