Evidence map›Paper›PMID 41226295›Full record

ArticleInternational journal of molecular sciences2025

Antiradical and Antioxidant Activity and Stimulation of Pancreatic Lipase by Extracts Obtained from Saponin-Rich Raw Materials: Experimental and In Silico Study.

Zbigniew Sroka, Karina Kapusta, Klaudia Suchańska, Wojciech Kołodziejczyk, Beata Żbikowska, Andrzej Gamian, Kacper Strzelczyk, Michał Gleńsk, Kamil Wojciechowski

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zbigniew SrokaDepartment of Pharmacognosy and Herbal Medicines, Wroclaw Medical University, Borowska 211a, 50-556 Wroclaw, Poland.ORCID 0000-0001-6618-017X
Karina KapustaDepartment of Chemistry and Physics, Tougaloo College, Tougaloo, MS 39174, USA.ORCID 0000-0001-8466-4098
Klaudia SuchańskaStudent Faculty of Pharmacy, Wrocław Medical University, Borowska 211, Wrocław, Poland.ORCID 0009-0003-9760-5240
Wojciech KołodziejczykDepartment of Chemistry, Physics and Atmospheric Sciences, Jackson State University, Jackson, MS 39217, USA.ORCID 0000-0002-7754-8969
Beata ŻbikowskaDepartment of Pharmacognosy and Herbal Medicines, Wroclaw Medical University, Borowska 211a, 50-556 Wroclaw, Poland.
Andrzej GamianDepartment of Immunology of Infectious Diseases, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Rudolfa Weigla 12, 53-114 Wrocław, Poland.ORCID 0000-0002-2206-6591
Kacper StrzelczykStudent Faculty of Pharmacy, Wrocław Medical University, Borowska 211, Wrocław, Poland.ORCID 0009-0002-7248-7586
Michał GleńskDepartment of Pharmacognosy and Herbal Medicines, Wroclaw Medical University, Borowska 211a, 50-556 Wroclaw, Poland.
Kamil WojciechowskiDepartment of Chemistry, University of Warmia and Mazury in Olsztyn, Pl. Łódzki 4, 10-721 Olsztyn, Poland.ORCID 0000-0001-7693-9469

Funding

Hirszfeld Institute of Immunology and Experimental Therapy 501-15National Institute of General Medical Sciences of the National Institutes of Health P20GM103476National Science Foundation OIA-2414445University of Warmia and Mazury Olsztyn 30.610.001-110Wrocław Medical University SUBZ.D110.23.029Wrocław Medical University SUBZ.D110.25.050
6 · The paper itself

Abstract

The effects of saponin-rich extracts on pancreatic lipase activity were examined. Horse chestnut seed and ginseng root extracts stimulated lipase activity the most, while ivy leaf and fenugreek seed extracts had an inhibitory effect. The strongest antiradical activity (ABTS

Indexed as

AntioxidantsLipasePancreasPlant ExtractsSaponinsAesculusAnimalsComputer SimulationFree Radical ScavengersMolecular Docking SimulationPanaxSeedsTrigonellaAntioxidantsFree Radical ScavengersLipasePlant ExtractsSaponinsantioxidantscomputational studylipase stimulationpancreatinplant extractsplant phenolssaponins

Identifiers

PMID41226295
PMCPMC12608017

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.